PedAM
Pediatric Disease Annotations & Medicines
| Disease | septicemia |
| Symptom | C0948600|organ failure |
| Sentences | 168 |
| PubMedID- 25692047 | The authors report a case of near-fatal sepsis with multiorgan failure resulting from a staphylococcal tampon-associated toxic shock syndrome, requiring a lengthy critical care admission. |
| PubMedID- 21258418 | A parainfluenza-3 outbreak in a sct unit: sepsis with multi-organ failure and multiple co-pathogens are associated with increased mortality. |
| PubMedID- 24167596 | Lipopolysaccharide (lps), a major cell wall component of gram-negative bacteria, is responsible for the overwhelming innate immune response of sepsis syndrome leading to multiple organ failure and death in septic patients 1. |
| PubMedID- 23372305 | Intra-abdominal sepsis leading to multiple organ failure accounts for most of the late deaths, indicating the importance of early haemodynamic stabilization, adequate debridement of devitalized tissue and wide drainage. |
| PubMedID- 25574232 | Studies have demonstrated that glutamine can effectively attenuate the rapid progression of sepsis that leads to multiple organ failure and eventually mortality (4,6–11). |
| PubMedID- PMC3952505 | The final diagnoses were severe sepsis with organ failure in 338 patients, nonsevere sepsis without organ failure in 340 patients, and no infection in 85 patients. |
| PubMedID- 22477519 | Thus, we have measured the proteolytic activity of both proteasomes and lysosomes in leg muscle biopsies from sepsis patients with multiple organ failure. |
| PubMedID- 23476738 | sepsis with multiple organ failure, myocardial infarction, and subdural bleeding were the main causes of death. |
| PubMedID- 26053561 | The patient responded to immunosuppression, but finally died from multi-organ failure due to sepsis 8 months after stem cell transplantation. |
| PubMedID- 23685543 | Multi-organ failure due to sepsis led to early death between six weeks and five months of age in spite of intensive care treatment. |
| PubMedID- 23241416 | The patient in that case was treated by hbo therapy but unfortunately the patient died of sepsis with multi-organ failure. |
| PubMedID- 26440517 | Finally, the most potent cox–2 inhibitors were tested for their ability to modulate cox–2 activity during acute inflammation in the lps induced sepsis model with multi organ failure. |
| PubMedID- 22769045 | Two had severe brain injury, and the other two developed sepsis with multiple organ failure during admission. |
| PubMedID- 23080091 | Mechanical support after failure of the initial medical treatment was necessary in 37% of patients; 29 (63.0%) patients from the gf group died, the cause of death being sepsis with multi-organ failure. |
| PubMedID- 21912446 | Two were from sepsis with multiple organ failure while the last was from pulmonary embolism in the outpatient setting. |
| PubMedID- 26011837 | Overall survival was only 29.8%, the main cause of death being severe sepsis with multiple organ failure(61.4%) and bronchopneumonia (52.6%). |
| PubMedID- 26425347 | This may play a role in inflammatory states, as for example sepsis with multi-organ failure, where tpe has been employed . |
| PubMedID- 22864954 | Severe sepsis leading to organ failure is the most common cause of mortality among critically ill patients. |
| PubMedID- 25557485 | Conclusions: the extent of organ failure in sepsis correlates directly with the existence of imbalanced innate and adaptive responses at the transcriptomic level. |
| PubMedID- 24054495 | Background: organ failure in sepsis accounts for significant mortality worldwide. |
| PubMedID- 23112976 | Shoshin beriberi can mimic sepsis with multiorgan failure and a high index of suspicion is required to diagnose this rapidly reversible condition. |
| PubMedID- 25126719 | Neonatal ev infections lead to a wide range of clinical manifestations, from mild febrile illness to severe, potentially fatal sepsis-like conditions with multiorgan failure. |
| PubMedID- 24349222 | Polymicrobial sepsis with concomitant multiple organ failure remains one of the leading causes of death in critically ill patients. |
| PubMedID- 21345232 | When sepsis is paired with organ failure, it is known as severe sepsis. |
| PubMedID- 26288730 | The mortality of nf is, depending on the study, up to 50% and is usually caused by a pronounced sepsis with secondary multi organ failure . |
| PubMedID- 21805225 | There is evidence that activation of coagulation in concert with inflammatory activation can result in microvascular thrombosis and thereby contribute to multiple organ failure in patients with severe sepsis 6. |
| PubMedID- 20374626 | Apc, commercialized as drotaa, is approved by both the american and european drug agencies as an adjunctive treatment of severe sepsis in patients with organ failure and/or at high risk of death. |
| PubMedID- PMC2963249 | Severe plasmodium falciparum malaria is a cause of icu in coming, appearing like in sepsis with multi - organ failure, resulting in high mortality 10-50%. |
| PubMedID- 24719758 | The mechanism by which aki itself could contribute to increased mortality remains not completely understood but volume overload, coagulation abnormalities, an increased incidence of sepsis with multiorgan failure, and cytokine or immune-mediated major organ dysfunction are possible explanations . |
| PubMedID- 22121360 | Seven patients had more than one diagnosis made (not including patients with organ failure as part of a sepsis syndrome or neutropaenic sepsis occurring on the background of chemotherapy for malignancy). |
| PubMedID- 22172797 | A sequential organ failure assessment was associated with infection or sepsis upon icu admission (area under the curve, 0.737 +/- 0.019; 95% ci, 0.748-0.825). |
| PubMedID- 23824895 | Despite advances in intensive care unit interventions, including the use of specific antibiotics and anti-inflammation treatment, sepsis with concomitant multiple organ failure is the most common cause of death in many acute care units. |
| PubMedID- 25887177 | The all-cause mortality rate was 14.5%, 27.3% and 36.2% at 7, 30 and 90 days, respectively (table 2).table 2patient outcomes and managementseverity of sepsisn (%)sepsis without organ failure214 (57.4)severe sepsis111 (29.8)septic shock48 (12.9)pitt bacteremia score0127 (34.0)1115 (30.8)265 (17.4)≥366 (17.7)all-cause mortality7-day54 (14.5)30-day102 (27.3)90-day135 (36.2)empiric antibiotic managementpenicillin plus aminoglycoside65 (17.3)cefuroxime-containing regimens63 (16.9)dicloxacillin-containing regimens62 (16.6)penicillin monotherapy52 (13.9)cefotaxime-containing regimens47 (12.7)other treatment73 (19.6)no treatment11 (2.9)inefficient treatment57 (15.3)definitive antibiotic treatment*penicillin plus aminoglycoside18 (4.8)dicloxacillin-containing regimens190 (51.0)penicillin monotherapy34 (9.1)cefuroxime-containing regimens29 (7.9)cefotaxime-containing regimens28 (7.6)other treatment62 (16.7)no treatment10 (2.7)inefficient treatment11 (2.9)median antibiotic treatment duration (interquartile range)$intravenous treatment (n = 351)10 days (5–15)total antibiotic treatment duration (n = 331)14 days (10–25)aminoglycoside treatment (n = 117)3 days (2–7)other managementreceived surgical treatment119 (31.9)treatment in intensive care unit (icu)/high dependency unit92 (24.7)treatment with vasopressors39 (10.5)ventilator treatment15 (4)examined with echocardiography134 (35.9)median length of stay (interquartile range)13 days (7–22)*data on definitive treatment lacking for two patients.$data is lacking on 22 patients for intravenous treatment duration and on 42 patients for total antibiotic treatment duration. |
| PubMedID- 20339175 | In conclusion, pon1 activity has decreased significantly in acute viral hepatitis, sepsis with multi organ failure and falciparum malaria patients. |
| PubMedID- 25780458 | Il-10 can reduce excessive inflammation in sepsis, and il-10-deficiency leads to multiple organ failure and increased mortality rates in mice (16). |
| PubMedID- 24124616 | Hospitalizations for severe sepsis with organ failure from 1997 to 2008 were extracted from taiwan’s national health insurance research database (nhird), and trends in sepsis incidence and mortality rates were analyzed. |
| PubMedID- 25408563 | Though acute success was 100%, one patient had recurrence of clinical vt the next day of procedure.one patient succumbed to sepsis with multiple organ failure. |
| PubMedID- PMC4033981 | Multiple organ systems failure) may need longer intravenous antibiotic therapy, and can be cured of life-threatening septicaemia with multiple organ failure by aggressive and co-coordinated management . |
| PubMedID- 25024994 | Severe sepsis with multiple organ failure remains the most frequent cause of morbidity and mortality after autologous or allogeneic hematopoietic stem cell transplantation (hsct). |
| PubMedID- 24834712 | We present a case of 66 year old patient who sustained bladder perforation at the time of tvt procedure and subsequently developed sepsis rapidly leading to multi-organ failure and triggering sequence of serious complications. |
| PubMedID- 22228975 | Results: although a transient response to initial treatment was detected, all four patients died of complications from gvhd: one from sepsis with multiple organ failure, one from gastrointestinal bleeding, and the other two from sepsis with gastrointestinal bleeding. |
| PubMedID- 21829646 | The causes of death of 35 prf patients included sepsis with multiorgan failure (29 patients), rejection (2), gastrointestinal hemorrhage (2), cardiac dysfunction (arrhythmia, 1), and pulmonary embolism (1). |
| PubMedID- 21852528 | Of the streptococcus dysgalactiae subspecies equisimilis strain re378, which was isolated from a patient suffering from multiple organ failure due to septicaemia, into both hind footpads of human cd46-expressing transgenic (tg) mice. |
| PubMedID- 24741225 | The severity of infection can range from a self-limiting febrile illness to a fulminant sepsis syndrome with multi-organ failure and death. |
| PubMedID- 23413151 | Objective: to compare the prognostic performance of the predisposition, infection, response and organ failure (piro) score with the traditional sepsis category and clinical judgement in high-risk and low-risk dutch emergency department (ed) sepsis populations. |
| PubMedID- 21501461 | Its management requires repeat operations and there are many risks, including life-threatening sepsis leading to multiple organ failure. |
| PubMedID- 23216871 | Although citrate did not perform worse in any post hoc subgroup, it appeared particularly beneficial in surgical patients, younger patients, patients with sepsis and in patients with more organ failure, suggesting either a protective role of citrate or harmful effects of heparin during inflammation. |
| PubMedID- 25907530 | Background: severe acute pancreatitis (sap) is associated with systemic inflammation, immunoparalysis, and sepsis, and may lead to vital organ failure and death. |
| PubMedID- 23935249 | Our study now shows that also sdma, another methylated form of l-arginine, is also significantly upregulated in critically ill patients, especially in conditions of sepsis, associated with inflammation and organ failure as well as a yet unrecognized indicator for mortality risk in medical icu patients. |
| PubMedID- PMC3363724 | Severe sepsis with multiorgan failure being seen in nearly one-half of ricu cases may decrease seizure threshold in these patients. |