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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Symptom C0856169|endothelial dysfunction
Sentences 7
PubMedID- 20606905 Context: diffused endothelial dysfunction in sepsis leads to an increase in systemic capillary permeability, the renal component manifesting as microalbuminuria.
PubMedID- 24430552 Elevated levels of plasma tnf-alpha are associated with microvascular endothelial dysfunction in patients with sepsis through activating the nf-kappab and p38 mitogen-activated protein kinase in endothelial cells.
PubMedID- 24700901 we used it in our patient as pf leptospira infection with superimposed sepsis is associated with endothelial dysfunction and propensity for systemic vascular thrombosis (venous and arterial) and received favourable results.
PubMedID- 23936333 We found that severe sepsis leads to in vivo endothelial dysfunction, which coincides with reduced cellular endothelial repair capacity.
PubMedID- 25279358 Rv systolic dysfunction in sepsis is directly associated with markers of endothelial dysfunction (endothelin 1, vascular cellular adhesion molecule 1) and directly related to the severity of sepsis .
PubMedID- 23506496 endothelial dysfunction associated with sepsis leads to impairment of microcirculation and cerebral metabolic uncoupling that may further reduce brain perfusion so that cbf becomes inadequate to satisfy brain cellular needs.
PubMedID- 21855287 Conclusion: both lv and rv systolic dysfunctions are prevalent in severe sepsis, being directly associated with markers of endothelial dysfunction.

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