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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Symptom C0026846|muscle wasting
Sentences 5
PubMedID- 25658432 Positive effects of hmb on muscle protein turnover in animal models of muscle wasting due to sepsis, age or disuse have been described .
PubMedID- 20677217 Because sepsis-induced muscle wasting is at least in part regulated by glucocorticoids, we also determined the influence of glucocorticoids on myostatin expression.
PubMedID- 23238742 The present results suggest that sepsis-induced muscle wasting is associated with reduced camkii activity and that tnfalpha may be involved in the regulation of camkii activity in skeletal muscle.
PubMedID- 21871000 muscle wasting in patients with sepsis, severe injury, and cancer is associated with increased transcription of several genes regulating different proteolytic pathways.
PubMedID- 20079455 sepsis-induced muscle wasting has severe clinical consequences, including muscle weakness, need for prolonged ventilatory support and stay in the intensive care unit, and delayed ambulation with risk for pulmonary and thromboembolic complications.

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