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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Symptom C0021079|immune suppression
Sentences 3
PubMedID- 24646167 Conclusions: these results suggest that immune suppression in sepsis may be closely linked to the development of aki and that scd25 or il-10 may be useful as novel biomarkers for the development of septic aki.
PubMedID- 21788440 These data further implicate trail-dependent immune suppression during sepsis and suggest trail neutralization may be a potential therapeutic target to restore cellular immunity in septic patients.
PubMedID- 21873557 Major features of sepsis-induced immune suppression include t-cell dysfunction, which is characterized by apoptosis of splenic t cells, increased cd4(+)foxp3(+) regulatory t cells (tregs), and suppression of type 1 helper t-cell response e.g., interferon-gamma (ifn-gamma) secretion in mice.

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