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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Symptom C0011570|depression
Sentences 11
PubMedID- 22761733 Cardiac depression in sepsis is associated with the increased morbidity and mortality.
PubMedID- PMC3672759 However, the care of the critically ill patient (that is, myocardial depression in sepsis, heart-lung interactions, and prediction of fluid responsiveness) is not covered in this textbook.
PubMedID- 22482045 The myocardial depression in sepsis may be attributed to a desensitization of β-ars due to an excess of catecholamines and to endotoxin action on the effects of the cardiac pacemaker current if on ionic channels.
PubMedID- 24887309 We hypothesized that myocardial depression in sepsis is global rather than right-sided; however, our findings suggest that a pac-derived rvef may reflect septic cardiomyopathy better than echocardiography and may have greater diagnostic and prognostic value in mechanically ventilated septic patients.
PubMedID- 25973949 Cardiac depression occurs in 40–50% of patients with severe sepsis and raises the mortality rate to 80–90% .
PubMedID- 23706109 In 1977, using pulmonary artery catheter thermodilution method measured left ventricular stroke work index, observed that not only was left ventricular depression common in patients with sepsis, but was also potentially reversible 2.
PubMedID- 22554063 Although left ventricular (lv) depression in sepsis was first reported decades ago .
PubMedID- 23691359 Release of cytokines (il1β, il-6, and tnfα), nitric oxide, endotoxins in setting of a gram negative bacteremia and sepsis leading to myocardial depression and ventricular dilatation 3 is another theory to explain srte (figure 1).
PubMedID- 26163554 Introduction of mechanical support, including extracorporeal cardiopulmonary resuscitation may be recommendable in cases of severe sepsis with myocardial depression resulting in haemodynamic collapse, however, the option of introduction of an invasive approach needs further examination.
PubMedID- 23894482 sepsis patients with myocardial depression are at a 50–70% greater risk of mortality than patients without cardiovascular complications .
PubMedID- 23438256 Risk factors include pre-ali depression, durations of stay and sepsis in the icu, and administration of high-dose opiates in the icu.

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