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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Symptom C0005779|coagulopathy
Sentences 17
PubMedID- 21822632 In an early study, hinshaw and colleagues 3 observed that heparin could prevent the consumptive coagulopathy associated with escherichia coli-induced sepsis in baboons but did not rescue the animals.
PubMedID- 23625756 Hypothetically, patients with thrombophilia may suffer from more severe coagulopathy in case of severe infection or sepsis, which may result in a more serious clinical course and an unfavorable outcome.
PubMedID- 23170801 Systemic consumptive coagulopathy in sepsis may exhaust both coagulant and anticoagulant factors, which may be manifested as prolonged plasma clotting time .
PubMedID- 25705426 Rtm is now under the spotlight, and a phase iii clinical trial evaluating its efficacy in severe sepsis patients with coagulopathy is now ongoing in the usa, south america, asia, australia, european union, and other countries.
PubMedID- 21247509 Protein c plays an important role in the coagulopathy associated with sepsis and probably also in the pathogenesis of sepsis-induced organ dysfunction.
PubMedID- 24512650 First, coagulopathy in sepsis is a dynamic process, evolving from subtle activation of coagulation to overt dic.
PubMedID- 25907781 Given that severe sepsis is associated with concurrent coagulopathy and endothelial disruption and damage, the aim of the present study was to investigate the association between coagulopathy, evaluated by whole blood teg, and endothelial activation and/or damage in patients with severe sepsis.
PubMedID- 26221544 We present a case where dabigatran etexilate caused severe coagulopathy in a patient with severe sepsis and acute renal failure in need of bilateral lower leg amputation.
PubMedID- 20628562 Baboons more closely resemble human being in endotoxin sepsis with typical coagulopathy and progressive multiorgan dysfunctions .
PubMedID- 26215804 Future efforts to ameliorate coagulopathy in sepsis should consider mechanisms that include platelet adherence and secretion.
PubMedID- 26082068 Methods: neisseria meningitidis (nm), the causative bacteria of meningococcal sepsis with coagulopathy in vivo, induces tf on monocytes and monocyte-derived mps.
PubMedID- 20727227 As microvascular thrombosis is felt to contribute to organ failure and coagulopathy in sepsis , epo could exacerbate this problem.
PubMedID- 22394653 A diagnosis of neonatal sepsis with disseminated intravascular coagulopathy was made and he was referred to our hospital.
PubMedID- 21317646 Conclusion: coagulopathy with sepsis or other variables, such as type of infectious source, may influence the efficacy of heparin therapy for sepsis.
PubMedID- 20224981 Truncation of operation with abdominal packing, bowel closure, external drainage of bile and pancreatic ducts, and rapid abdominal closure with planned subsequent completion laparotomy should be considered in pancreatic operations when patients risk intraoperative acidosis, hypothermia, and coagulopathy due to sepsis or hemorrhage.
PubMedID- 21769210 coagulopathy in sepsis ensues in concomitance and as result of the deranged inflammatory response.
PubMedID- 23555024 Several studies have characterized the coagulopathy in sepsis and experimental human , and animal – endotoxemia by these tests.

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