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PedAM

Pediatric Disease Annotations & Medicines




Disease septicemia
Symptom C0001623|adrenal insufficiency
Sentences 5
PubMedID- 25255427 Single-dose etomidate increased the risk of adrenal insufficiency in patients with sepsis (eight studies; rr, 1.42; 95% ci, 1.22-1.64; p < .00001).
PubMedID- 23949462 Objective: to determine the frequency of adrenal insufficiency in children diagnosed with sepsis that were staying in pediatric intensive care units and to establish the association between adrenal function and the use of vasoactive drugs, mechanical ventilation time and mortality.
PubMedID- 20626892 The use of prolonged low-dose corticosteroid was justified in the landmark annane and colleagues trial on the basis that "severe sepsis may be associated with relative adrenal insufficiency or systemic inflammation-induced glucocorticoid receptor resistance..." .
PubMedID- 21545846 Background & aims: relative adrenal insufficiency (ai) occurs in patients with cirrhosis with sepsis, but not with variceal bleeding.
PubMedID- 24562381 Together, these results suggest that dopaminergic d1-agonists mimic the anti-inflammatory potential of electroacupuncture and can provide pharmacological advantages to control sepsis in patients with adrenal insufficiency and in a clinically relevant time frame (supplementary fig.3e).

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