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PedAM

Pediatric Disease Annotations & Medicines




Disease schizophrenia
Symptom C0086439|hypoactivity
Sentences 4
PubMedID- 24731078 The superior temporal sulcus hypoactivity and frontopolar hyperactivity of patients with schizophrenia in social rejection situations may suggest the presence of mentalizing deficits in negative social situations and inefficient processes of socially aberrant stimuli, respectively.
PubMedID- 22570726 Since the negative symptoms of schizophrenia are associated with hypoactivity of dopaminergic systems, smoking may lessen negative symptoms by increasing dopamine in the nucleus accumbens .
PubMedID- 22347412 Since the negative symptoms of schizophrenia are associated with hypoactivity of dopaminergic systems, smoking may lessen negative symptoms by increasing dopamine in the nucleus accumbens .
PubMedID- 25091423 Therefore, the hypothetically decreased 5ht2a receptors on pyramidal neurons in the limbic pfc in residual schizophrenia with subsequent hypoactivity of these neurons might lead to the increased rdna transcription in drn neurons suggested by our study.

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