PedAM
Pediatric Disease Annotations & Medicines
| Disease | schizophrenia |
| Symptom | C0086132|depressive symptoms |
| Sentences | 25 |
| PubMedID- 21254789 | In addition, treating depressive symptoms in patients with schizophrenia is an important component of suicide risk reduction. |
| PubMedID- 26257524 | However, the current level of evidence supporting their use for the management of anxiety and depressive symptoms in patients with schizophrenia is limited, although apa guidelines76 suggest that bdzs may be helpful for managing anxiety during the stable phase of treatment and for acute agitation. |
| PubMedID- 25367164 | Objective: to assess the benefit of short-term treatment with the atypical antipsychotic asenapine versus placebo on depressive symptoms in patients with acute schizophrenia in an exacerbated state. |
| PubMedID- 23199176 | A key issue in the differential diagnosis of depressive symptoms in patients with schizophrenia is disentangling the contribution of negative symptoms. |
| PubMedID- PMC4034064 | The use of aripiprazole may be efficacious in treating depressive symptoms in patients with schizophrenia and bipolar disorder . |
| PubMedID- 24955752 | Four similarly designed, placebo-controlled studies of lurasidone were identified that included the montgomery–åsberg depression rating scale (madrs) for evaluation of changes in depressive symptoms in patients with schizophrenia (table 1). |
| PubMedID- 22044873 | Emergence of depressive symptoms in schizophrenia results in a deteriorating course and poor prognosis. |
| PubMedID- 21177241 | Current classifications of depressive symptoms in patients with schizophrenia include: major depressive episodes that occur in patients with schizophrenia and are not classified as schizoaffective disorder, schizoaffective disorder, and schizophrenia with subsyndromal depression in which depressive symptoms do not meet criteria for major depression. |
| PubMedID- 22003284 | This highlights the relevance of recognizing depressive symptoms in patients with schizophrenia and the need for close monitoring. |
| PubMedID- 23825848 | It may be that ssris are the preferred class of medications for treating depressive symptoms in patients with schizophrenia, but further comparative studies are needed before this conjecture can be stated with certainty. |
| PubMedID- 25241757 | However, the data do not clarify whether depressive symptoms in schizophrenia occur as a dimension of schizophrenia or as symptoms of major depression that is comorbid with schizophrenia. |
| PubMedID- 21253021 | They demonstrated that ssr 103800 elevates central glycine levels in the prefrontal cortex, and it exhibits potential therapeutic activity in animal models considered representative of the positive, cognitive, and depressive symptoms observed in patients with schizophrenia . |
| PubMedID- 20005675 | Impaired hedonic reward processing might contribute to the development of depressive symptoms in patients with schizophrenia, but it is not directly associated with self-rated anhedonia. |
| PubMedID- 25453735 | Post hoc analysis of four pooled short-term studies showed significantly better effects on improving depressive symptoms associated with schizophrenia in patients treated with lurasidone as compared to patients treated with placebo. |
| PubMedID- 22121030 | These results suggest that adjunct treatment with escitalopram, but not citalopram, may enhance the effect of a subtherapeutic dose of risperidone on positive, negative, cognitive, and depressive symptoms in schizophrenia, yet without increased eps liability. |
| PubMedID- 25834445 | To our knowledge, the effectiveness of adjunctive antidepressants on the depressive symptoms in patients with schizophrenia varies considerably. |
| PubMedID- 25893497 | Due to the complex and heterogeneous picture of depressive symptoms in schizophrenia, the application of standardized assessment tools is recommended. |
| PubMedID- 25786240 | In japan, nirs has been used as a tool in assisting in the diagnosis of mdd, bipolar disorder, and schizophrenia with depressive symptoms as a clinical trial for several years; however, it is still unclear whether nirs signal changes during vft are state- or trait-dependent, the extent to which they are affected by antidepressant treatment, and whether nirs could be a neural predictor of treatment response. |
| PubMedID- 24332387 | Background: we examined the relationship between subjective well-being and depressive symptoms in patients with treatment-resistant schizophrenia before and after treatment with clozapine to contribute to the growing body of research regarding the determinants of patients' perspective of their own well-being in schizophrenia. |
| PubMedID- 24794100 | Atypical antipsychotics such as quetiapine, aripiprazole, olanzapine, and risperidone have been shown to be helpful in addressing a range of anxiety and depressive symptoms in individuals with schizophrenia and schizoaffective disorders, and have since been used in the treatment of a range of mood and anxiety disorders. |
| PubMedID- 24608149 | Background: depressive symptoms in schizophrenia are common, more so in women, but associated neurobiological mechanisms are poorly understood. |
| PubMedID- 26379600 | Results of reduced activity in the right accumbens nucleus of those schizophrenia participants with more depressive symptoms. |
| PubMedID- 25887360 | We have recently reported in a randomized, placebo-controlled trial, a safe, rapid, and long-lasting improvement of positive, negative, anxiety, and depressive symptoms in patients with schizophrenia after a single intravenous injection of the nitric oxide (no) donor sodium nitroprusside (snp) 1. |
| PubMedID- 22003295 | For example, the presence of depressive symptoms in patients with schizophrenia is associated with poorer treatment outcomes. |
| PubMedID- 24681810 | In this study, quetiapine xr was noninferior to risperidone at reducing depressive symptoms in patients with schizophrenia or schizoaffective disorder. |
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