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PedAM

Pediatric Disease Annotations & Medicines




Disease schizophrenia
Symptom C0004936|mental disorders
Sentences 8
PubMedID- 21635859 Clinical trials involving children and adolescents have demonstrated the efficacy of aripiprazole in bipolar disorders, schizophrenia, mood disorders associated with pervasive developmental disorders, in tics and tourette's.
PubMedID- 23358230 Severity of nicotine dependence, smoking prevalence, and the likelihood of success of quit attempts are much worse in schizophrenia than in patients with other mental disorders or smokers in the general population.
PubMedID- 24791229 6 in the present study, 10.79% of mental disorders occurred due to schizophrenia, schizotypal, and delusional disorders.
PubMedID- 24433461 Based on our preliminary data, among the 4,000 project 686 patients registered in liuyang municipality, hunan province, as having severe mental disorders -- most of them schizophrenia patients -- only approximately 70% obtained their free antipsychotics in the previous two months, and for those who got medications, no information exists regarding actual use.
PubMedID- 20520290 From an ongoing study of severe mental disorders, 280 patients with schizophrenia and bipolar disorder who were prescribed psychopharmacological agents were included.
PubMedID- 25501035 We sought to identify potential overlap between the ders and genetic loci conferring risk for 13 neurodevelopmental disorders, starting with schizophrenia, specifically the 108 genome-wide significant loci from the latest psychiatric genomics consortium genome-wide association study (gwas) of over 150,000 subjects 27. specifically, 42 loci (of the 108 loci, 38.9%) overlapped at least 1 der which was statistically significant via permutation analysis (p=0.0013, see methods, table 2).
PubMedID- 23912945 Surprisingly, we discovered that top3β is an rna topoisomerase that binds multiple mrnas related to neuronal function and mental disorders, promotes expression of a schizophrenia-related gene in synapse, and is essential for normal synapse formation.
PubMedID- 23011268 Disrupted-in-schizophrenia-1 (disc1) is associated with mental disorders, including major depression.

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