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PedAM

Pediatric Disease Annotations & Medicines




Disease purpura
Symptom C0040034|thrombocytopenia
Sentences 11
PubMedID- 26400844 For example, eltrombopag (promacta, glaxosmithkline, london, uk), originally approved using orphan drug designation in 2008 for the treatment of thrombocytopenia in patients with immune thrombocytopenic purpura, was later approved for thrombocytopenia in patients with hepatitis c, a non-rare condition.
PubMedID- 24711916 In this study we have explored the relationship between tpo and cmpl in platelets and megakaryocytes of 43 patients with thrombocytopenia due to idiopathic thrombocytopenic purpura (itp), bone marrow hypoplasia, myelodysplastic syndromes (mds), and familial thrombocytopenia.
PubMedID- 20650736 A high ipf% does not substantiate hyperdestructive thrombocytopenia but a diagnosis of idiopathic thrombocytopenic purpura should be questioned if ipf% is not raised.
PubMedID- 24033710 Our patient, a 26-year-old man, had attacks of thrombotic thrombocytopenic purpura (ttp) with thrombocytopenia and a urine dipstick positive for hemoglobin (4+), often as the only sign of hemolytic activity.
PubMedID- 22970399 The patient also developed thrombocytopenia and was diagnosed with idiopathic thrombocytopenia purpura (itp).
PubMedID- 25884311 When thrombocytopenia rapidly develops in patients with idiopathic thrombocytopenic purpura immediately following pregnancy, the possibility of a thrombogenic state and differential diagnosis, including antiphospholipid syndrome and collagen vascular disease, should be considered.
PubMedID- 24987409 Five days later, she developed a syndrome that was characteristic of thrombotic thrombocytopenic purpura with fever, thrombocytopenia, microangiopathic hemolysis, renal impairment and neurological dysfunction in the form of confusion and coma.
PubMedID- 21629797 We report a case of 19-year-old previously healthy female that presents with anemia and thrombocytopenia diagnosed with thrombotic thrombocytopenic purpura that was treated successfully with plasmapheresis and corticosteroids.
PubMedID- 23390027 When a patient presents with unexpected microangiopathic hemolytic anemia and thrombocytopenia, the diagnosis of thrombotic thrombocytopenic purpura (ttp) is often considered.
PubMedID- 23720092 Introduction: bleeding risk because of thrombocytopenia in patients with thrombotic thrombocytopenic purpura (ttp) often causes concern during placement of the central venous catheter for plasma exchange.
PubMedID- 22493563 It is highly desirable that life threatening conditions like thrombotic thrombocytopenic purpura and other causes of thrombocytopenia should be excluded.

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