PedAM
Pediatric Disease Annotations & Medicines
| Disease | psoriasis |
| Symptom | C1867449|psors1 |
| Sentences | 3 |
| PubMedID- 22739795 | A very strong association of psoriasis with hla-cw6 (psors1) has long been established, providing unambiguous evidence of the importance of genetic variation in psoriasis. |
| PubMedID- 22437317 | Sequencing the dutpase in 708 cases and 349 controls, we found that herv-k dutpase variants at psors1 are strongly associated with psoriasis but that this association was not as strong as the association of psoriasis with hla-c*06:02. to determine whether dutpase variants were associated with psoriasis independent of psoriasis-associated hla alleles, we determined the ld between the herv variants and these hla alleles and identified hla-c*06:02 and hla-b*57:01 as the most likely potential confounders. |
| PubMedID- 22217737 | It is important to note that the cdsn gene is located in psors1, one of the major psoriasis (ps) susceptibility loci, and polymorphisms in this gene have been associated with ps in some populations (capon et al., 2004; helms et al., 2005; jenisch et al., 1999). |
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