PedAM
Pediatric Disease Annotations & Medicines
| Disease | psoriasis |
| Symptom | C0037284|skin lesion |
| Sentences | 7 |
| PubMedID- 26474319 | Importantly, s. aureus is detected in about 50% of skin lesions in patients with psoriasis , and is associated with a higher pasi score . |
| PubMedID- 22063458 | The relationship between quality of life (qol) and skin lesion improvement due to psoriasis treatment has been recently underlined. |
| PubMedID- 23090423 | Because of the development of hyperkeratotic skin lesions consistent with guttate psoriasis, the infliximab treatment was discontinued. |
| PubMedID- 24727542 | Increased chemerin levels are found in the skin lesions of lupus and acute psoriasis and in the kidneys of patients with severe lupus nephritis, which is associated with the tissue infiltration of pdcs, suggesting that chemerin may play a pro-inflammatory role in autoimmune diseases, possibly by mediating pdc chemotaxis.1,6,7 however, several studies have also demonstrated that the administration of exogenous chemerin exerts potential anti-inflammatory activities in experimental peritonitis and acute lung injury.8,9 in addition, several synthetic peptides derived from the c-terminal domain of human or mouse pro-chemerin were reported to display significant bioactivity.8,10,11 for example, the chemerin15 (c15) peptide was shown to ameliorate zymosan-induced peritonitis, which could be due to its capacity to enhance macrophage phagocytosis of microbial particles and apoptotic cells.8,11 however, another study failed to detect any activity of the c15 peptide.9 it is still unknown whether these peptides are generated in vivo due to the lack of a detection assay. |
| PubMedID- 20943046 | The role of etanercept on the expression of markers of t helper 17 cells and their precursors in skin lesions of patients with psoriasis vulgaris. |
| PubMedID- 20333526 | Expression of th1 and th2 cytokine-associated transcription factors, t-bet and gata-3, in peripheral blood mononuclear cells and skin lesions of patients with psoriasis vulgaris. |
| PubMedID- PMC4582085 | Finally, they investigated the skin lesions of patients with psoriasis and observed significantly increased il-33 expression compared to that in the skin of healthy volunteers . |
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