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PedAM

Pediatric Disease Annotations & Medicines




Disease psoriasis
Symptom C0011603|skin inflammation
Sentences 3
PubMedID- 23151849 These results show for that cd8+ t cells can orchestrate skin inflammation with psoriasis-like pathology in response to constitutive ras activation in keratinocytes, and this is primarily mediated through ifn-γ.
PubMedID- 26217343 Th1- and th1/th17-mediated skin inflammation leading to psoriasis or cutaneous delayed-type hypersensitivity reactions could be treated successfully by immune deviation approaches targeting t helper cell polarization and inducing immune deviation (25, 26, 28).
PubMedID- 25039885 Il-17 stimulates the keratinocytes to produce psoriasis-associated molecules, eventually leading to chronic skin inflammation.

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