PedAM
Pediatric Disease Annotations & Medicines
| Disease | proteinuria |
| Symptom | C0151650|renal fibrosis |
| Sentences | 4 |
| PubMedID- 21755055 | Although transgenic overexpression of the prorenin, a major ligand for the prr, in rats does not cause renal fibrosis, it leads to myocardial hypertrophy, proteinuria, and hypertension . |
| PubMedID- 25954204 | Interestingly, transgenic overexpression of the prorenin in rats does not cause renal fibrosis, whereas leads to myocardial hypertrophy, proteinuria, and hypertension (peters et al., 2008). |
| PubMedID- 23717698 | As seen in the hamster model, we also suspect that over time there is a progressive obsolescence of the glomeruli, tubular atrophy, interstitial inflammation, and renal fibrosis associated with this proteinuria , , . |
| PubMedID- 25363471 | A suitable threshold may be egfr <40 ml/min/1.73 m2, although some centers apply a higher cut-off (e.g., 60 ml/min/1.73 m2) and some centers also stipulate a protein/creatinine ratio ≥0.3 when defining renal dysfunction, although it should be noted that neither egfr nor proteinuria correlate with renal fibrosis on biopsy . |
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