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PedAM

Pediatric Disease Annotations & Medicines




Disease primary myelofibrosis
Symptom C0001815|myeloid metaplasia
Sentences 5
PubMedID- 21224796 Aim: in this paper we retrospectively analyzed prospectively-collected data on our myelofibrosis with myeloid metaplasia (mmm) patients who underwent splenectomy.
PubMedID- 20615740 Objective: lenalidomide (ldm) is an immunomodulatory and anti-angiogenic drug which has been shown to be effective in several haematological disorders (multiple myeloma mm, myeloid metaplasia with myelofibrosis mf and myelodysplastic syndrome mds).
PubMedID- 22282696 Increase in fibrosis is due to liberation of cytokines such as tgf-β and pdgf from dysplastic megakaryocytes.15 the differential diagnosis includes myelofibrosis with myeloid metaplasia, chronic myelocytic leukemia and acute megakaryocytic leukemia.
PubMedID- 24880208 Essential thrombocytosis (et) falls under the umbrella of myeloproliferative disorders, which also includes chronic myelogenous leukemia, polycythemia vera, and myelofibrosis with myeloid metaplasia.
PubMedID- 20359349 Clonal dysregulation linked to myeloproliferative neoplasms (mpn) arising from acquired mutations in the haematopoietic progenitor cells lead to a wide range of clonal haematological malignant diseases including polycythemia vera (pv), essential thrombocythemia (et), myeloid metaplasia with myelofibrosis (mmm), chronic myelomonocytic leukemia (cmml), chronic myelogenous leukemia (cml), hypereosinophilic syndrome (hes), and systemic mast cell disease (smcd)1.

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