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PedAM

Pediatric Disease Annotations & Medicines




Disease portal hypertension
Symptom C0020532|hypersplenism
Sentences 18
PubMedID- 25535428 Patients with myelo- and lymphoproliferative disorders can be anaemic due to increased haemolysis or hypersplenism as a consequence of cirrhosis and portal hypertension.
PubMedID- 23420139 While in some patients the disease remained static, in a larger proportion a more severe disease developed characterized by portal hypertension, the latter leading to hypersplenism with neutropenia and thrombocytopenia and, in some cases, to ascites.
PubMedID- 23177370 Background: consequences of extrahepatic portal vein obstruction (ehpvo) include variceal bleeding and hypersplenism due to portal hypertension, as well as metabolic abnormalities secondary to impaired portal venous circulation.
PubMedID- 22111083 Among 19 patients who survived over 10 years after kpe, 6 (31.6%) patients suffered from portal hypertension; 2 with hypersplenism, and 4 with variceal bleeding.
PubMedID- 22540086 In addition, the underlying cirrhosis present in most patients may lead to portal hypertension with hypersplenism, platelet sequestration, varices and gastrointestinal bleeding, hepatic encephalopathy, hypoalbuminemia, differential drug binding and distribution, and altered pharmacokinetics, limiting the selection and adequate dosing of most cytotoxic agents.
PubMedID- 20961440 Life-threatening hypersplenism due to idiopathic portal hypertension in early childhood: case report and review of the literature.
PubMedID- 25538966 Common indications of pse include hypersplenism with portal hypertension, hereditary spherocytosis, thalassemia, autoimmune hemolytic anemia, splenic trauma, idiopathic thrombocytopenic purpura, splenic hemangioma, and liver cancer.
PubMedID- 22277708 hypersplenism due to portal hypertension: retrospective evaluation of 17 patients treated by splenic embolization.
PubMedID- 20846792 In the present study, rna interference specific to pik3r1 was employed to investigate its inhibitive effects on the activity of mphi associated with hypersplenism due to portal hypertension (hs-pht).
PubMedID- 24741213 Mitra shunt (spleen preserving, side to side lieno-renal shunt) for portal hypertension with hypersplenism in early infancy.
PubMedID- 25680200 Cfld is characterized by cirrhosis and patients often present with splenomegaly, hypersplenism and complications of portal hypertension, including variceal bleeding and ascites .
PubMedID- 23454561 The incidence of hypersplenism in patients with cirrhosis and portal hypertension is high.
PubMedID- 25702511 Digestive varices and hypersplenism due to portal hypertension are often controllable via symptomatic treatment.
PubMedID- 25788181 Beta-blocker therapy ameliorates hypersplenism due to portal hypertension in children.
PubMedID- 23275773 The second etiology is much more common and is related to hypersplenism due to portal hypertension as a result of oxaliplatin-induced hepatic sinusoidal injury .
PubMedID- 22087192 This is evidenced by the fact that thrombocytopenia in cirrhotic patients is not only attributed to hypersplenism due to portal hypertension but also resulted from decreased thrombopoeitin and interleukin-11 1.
PubMedID- 20407867 This study examined the mrna expression of nalp3 in the spleen of the mice with hypersplenism due to portal hypertension (ph).
PubMedID- 20927629 Methods: case 1 was an 11-year-old boy diagnosed with rupture of the esophageal varices and hypersplenism due to congenital extrahepatic portal hypertension.

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