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PedAM

Pediatric Disease Annotations & Medicines




Disease portal hypertension
Symptom C0019214|hepatosplenomegaly
Sentences 3
PubMedID- 24501543 Potential complications from hepatosplenomegaly include portal hypertension and variceal bleeding, whereas extramedullary hematopoiesis outside the spleen and liver - depending on the affected organ - may result in intracranial hypertension, spinal cord compression, pulmonary hypertension, pleural effusions, lymphadenopathy, skin lesions, and/or exacerbation of abdominal symptoms.
PubMedID- 24886628 An abdominal ultrasound confirmed a homogeneous hepatosplenomegaly without signs of portal hypertension.
PubMedID- 26313777 Imaging studies may demonstrate hepatosplenomegaly, signs of portal hypertension, focal calcification in 20% of tumors, and can serve to categorize the disease as either early (with nodular bilobar peripheral tumor distribution) or late (with a diffuse confluent tumor appearance).6 in particular, mri may detect the hallmark features of hehe, which consist of peripheral confluent masses with capsular retraction and a halo or target enhancement pattern.5 in a comprehensive literature review of 402 patients, mehrabi et al determined that 87% of patients presented with multifocal bilobar disease, with extrahepatic involvement in 36.6% of cases.

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