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PedAM

Pediatric Disease Annotations & Medicines




Disease pertussis
Symptom C0010200|cough
Sentences 37
PubMedID- 26412843 Only one study has evaluated symptoms related to pertussis in adults with acute persistent cough in primary care.
PubMedID- 23092514 Licensed in the mid-1940s, the first whooping cough vaccines consisted of whole-cell inactivated b. pertussis (wp), and their use led to a dramatic decrease in disease incidence by the mid-1960s (2,3).
PubMedID- 23249233 Whooping cough, due to bordetella pertussis and bordetella parapertussis, is an important cause of childhood morbidity and mortality.
PubMedID- 24721229 Infection with b holmesii is frequently misidentified as being with b pertussis, the cause of whooping cough, because routine diagnostic tests for pertussis are not species-specific.
PubMedID- 21955853 pertussis (whooping cough) infection is most serious in infants under 6 months of age: 1 in 200 of these infants will die as a result of complications, such as brain damage .
PubMedID- 24696568 Case study on the effect of basti in the management of cough due to pertussis is also quite interesting.
PubMedID- 22368426 Diphtheria, pertussis (whooping cough), and tetanus vaccine induced recurrent seizures and acute encephalopathy in a pediatric patient: possibly due to pertussis fraction.
PubMedID- 25874411 Findings suggest high prevalence of pertussis among children with persistent cough at a health facility and it was marked in children >59 months of age, suggesting the possibility of waning immunity.
PubMedID- 26375454 Whooping cough due to bordetella pertussis is increasing in incidence, in part due to accumulation of mutations which increase bacterial fitness in highly vaccinated populations.
PubMedID- 26358588 pertussis (whooping cough) is the most common vaccine-preventable disease, and despite widespread vaccination, the circulation of bordetella pertussis, the causative agent of pertussis, has increased in many countries (1–3).
PubMedID- 20736473 Articles were selected that included children older than 5 years, adolescents, or adults and confirmed the diagnosis of pertussis among patients with cough illness (of any duration) with an a priori-defined accepted reference standard.
PubMedID- 23574624 The natural history of the cough with pertussis or a post viral syndrome is natural resolution.
PubMedID- 20437007 The authors describe the case of a 36 day old infant, brought to the emergency room due to respiratory distress and cyanosing cough, admitted with suspected pertussis infection complicated by bacterial pneumonia, having begun large spectrum antibiotics.
PubMedID- 26129684 pertussisproteingeneb-cell epitopechildren with whooping coughpertussis toxin subunit 4 precursorptxs4cfgkdlkrpgsspmep.69a protein (pertactin)prnlwyaesnalskrlgep.69a protein (pertactin)prnavvhlqlatirrgdafilamentous hemagglutininfhabfaadlrtvyakqadqbifunctional hemolysin-adenylate cyclaseprecursorcyaahaanqavdqagieklouter membrane porin protein precursoromppfgvntfadgfkansychildren who received the the dtpa2 vaccinebifunctional hemolysin-adenylate cyclaseprecursorcyaadqtvsgleigldrgvtracheal colonization factortcfaasnglrikddgtnsmthe table shows the sequence of target epitopes specifically recognized in serum (10/10) children with whooping cough (n = 6 peptides) and in serum from children who receivedthe diphtheria, tetanus, pertussis acellular 2 components (dtpa2) vaccine (2 peptides).
PubMedID- 22940441 Bordetella pertussis, the cause of whooping cough, is highly contagious.
PubMedID- 24219484 Although there is a high uptake of vaccinations providing protection against bordetella pertussis, the main cause of whooping cough, there has been an increase in the incidence of notifications of the disease in the uk and other developed countries in recent years.
PubMedID- 24075918 pertussis (whooping cough) is a severe infectious disease in infants less than 6 months old.
PubMedID- 26257822 Although some medications are available, there is no proven effective therapy for patients with prolonged cough attributed to pertussis .
PubMedID- 26022662 Here, we present a comprehensive account of pertussis (whooping cough) transmission in the united states during the early vaccine era.
PubMedID- 23972198 Clinical differentiation of pertussis from other causes of acute persistent cough is difficult.
PubMedID- 23596573 Diphtheria-tetanus-pertussis (whooping cough) (dtp) vaccine in 1955, killed polio vaccine in 1958, and inactivated vaccine for typhoid fever in 1960 were used.
PubMedID- 26278132 The resurgence of pertussis (whooping cough) in the past two decades has been the cause of much concern, with the number of reported cases in 2012 in the united states being the highest in fifty years1.
PubMedID- 24917600 The resurgence of pertussis (whooping cough) in countries with high vaccination coverage is alarming and invites reconsideration of the use of current acellular pertussis (ap) vaccines, which have largely replaced the old, reactogenic, whole-cell pertussis (wp) vaccine.
PubMedID- 21034844 pertussis (whooping cough) is one of the commonest vaccine preventable diseases in the uk, despite vaccination coverage being maintained for the last 15 years at over 90% among infants and the addition of a pre-school booster to the uk national immunisation programme in 2001.
PubMedID- 21738546 It was found that pertussis was the cause of the cough in 13-20% of adolescents and adults with non-specific cough continuing for over a week22).
PubMedID- 24599531 Serum samples and nasopharyngeal swabs (n = 503) were collected at the same time from patients presenting with cough illness suspected of being pertussis and tested by the pt elisa and culture and/or rt-pcr, respectively.
PubMedID- 21985340 cough as a result of a b. pertussis infection usually leads to paroxysmal episodes of coughing with a characteristic inspiratory whoop, especially in children.
PubMedID- 25093268 The recent epidemics of pertussis (whooping cough) in parts of the usa and australia have led to the largest numbers of annual cases reported in over half a century.
PubMedID- 23370334 pertussis (whooping cough) is still a major public health problem,1 even in countries with high rates of vaccination coverage as italy.
PubMedID- 23255856 We evaluated all infants clinically suspected of pertussis infection because of a cough lasting at least 2 weeks with at least one of the following symptoms: paroxysmal coughing; inspiratory whooping; post-tussive vomiting or apnea without other known cause.
PubMedID- 26468043 This cross-sectional study evaluated the prevalence of serologically confirmed pertussis in adults with prolonged cough in malaysia, taiwan and thailand.
PubMedID- 22794120 The resurgence of pertussis (whooping cough) in australia has attracted community concern, especially with recent deaths in two infants from the australian state of new south wales (nsw) .
PubMedID- 25316461 Despite reports of an association between prolonged cough in adults with the b. pertussis infections, adolescent and adult pertussis remains underestimated and a high number of physicians fail to diagnose cases.41-43 it is still difficult to decide whether the increasing number of cases in this age group, is due to enhanced surveillance or there is a real change.
PubMedID- 26130965 Considering this aspect, the actual proportion of korean adolescents and adults with chronic cough that is attributable to pertussis could be even higher than that indicated in the study results.
PubMedID- 23496900 The purpose of the present study was to identify a means of rapidly distinguishing pertussis from other causes of illness involving cough in daily clinical practice without waiting for serological or culture results.
PubMedID- 21747424 pertussis (whooping cough) epidemiology in waikato, new zealand: 2000-2009.
PubMedID- 24768867 We applied our method to pertussis (whooping cough) in sweden, where vaccination was discontinued from 1979 to 1995.

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