PedAM

Pediatric Disease Annotations & Medicines

Disease	periodontitis
Symptom	C0009450\|infection
Sentences	16
PubMedID- 21957382	Moreover, it has been observed in animal models that infection with gram-negative periodontitis-associated micro-organisms may adversely affect pregnancy outcomes.
PubMedID- 23755300	Treponema denticola is a key pathogen in the polymicrobial infection associated with chronic periodontitis , .
PubMedID- 26313005	Porphyromonas gingivalis, aggregatibacter actinomycetemcomitans, and treponema denticola / prevotella intermedia co-infection are associated with severe periodontitis in a thai population.
PubMedID- 26477831	Denticola) of the 120 in vitro compounds in the saliva from a periodontitis patient with confirmed infection with p.
PubMedID- 22368370	4 there is an approximate three-fold amplification of the rate of marginal radiographic bone loss (0.19 mm/year vs 0.06 mm/year) for teeth in periodontitis-prone patients with an endodontic infection compared to teeth without an infection.
PubMedID- 22509455	It has been noted that poor periodontal health characterized by gingivitis and chronic periodontitis may be associated with h. pylori infection and considered as a potential reservoir of these bacteria .
PubMedID- 20728711	This study investigated the microbial profile and the levels of endotoxin found in primary root canal infection with apical periodontitis, determined their antigenicity against macrophages through the levels of interleukin (il)-1beta and tumor necrosis factor alpha (tnf-alpha), and evaluated their relationship with clinical and radiographic findings.
PubMedID- 21496656	This study investigated target gram-negative bacterial species and endotoxins in primary endodontic infection with apical periodontitis, determined their antigenicity against macrophages through the levels of pge(2), and evaluated their relationship with clinical findings.
PubMedID- 26295020	On the other hand, when apical periodontitis is associated with tooth infection, regenerative endodontic treatment procedure is not considered.
PubMedID- 21523231	Specifically, p. gingivalis-derived gingipains (cysteine proteases) which include two arginine residue-specific enzymes, rgpa and rgpb, and a lysine residue-specific enzyme, termed kgp (16–18), have been shown to exert pathophysiological effects through cleavage or degradation of host proteins, such as cd14 on human monocytes (19) and gingival fibroblasts (20), icam-1 on human oral epithelial cells (21), and secretory leukocyte protease inhibitor (slpi) in gingival tissue of periodontitis associated with p. gingivalis infection (22).
PubMedID- 23152922	On the one hand, not every case of diagnosed apical periodontitis is necessarily associated with microbial infection 5, and on the other hand several reasons could be responsible for the inability to detect present microorganisms in some cases with neither of the methods.
PubMedID- 20170537	Gene coding for the ligand-binding chain of interferon gamma receptor 1, a cytokine that plays a pivotal role in defense against infection, was significantly associated with periodontitis in combination with smoking .
PubMedID- 25722922	The clinical characteristics of periodontitis result from a microorganism infection and the host response.
PubMedID- 24781742	While periodontitis is primarily associated with infection by pathogenic bacteria, such as actinobacillus actinomycetemcomitans and p. gingivalis, herpesviruses have also been implicated (35–37).
PubMedID- 23030239	Ndm consumption by mice attenuated the severity of experimental periodontitis compared with a mixed infection without ndm treatment.
PubMedID- 22595105	This study investigated the correlation between different clinical signs/symptoms and radiographic features according to the levels of interleukin (il)-1beta, tumor necrosis factor alpha (tnf-alpha), il-6, il-10, prostaglandin e(2) (pge(2)), and their networks produced by endodontic content-stimulated macrophages collected from primary endodontic infection with apical periodontitis (peiap).

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