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PedAM

Pediatric Disease Annotations & Medicines




Disease pancreatic cancer
Symptom C0149521|chronic pancreatitis
Sentences 29
PubMedID- 21510309 This study aimed to identify a high risk group for developing pancreatic cancer associated with chronic pancreatitis, particularly the presence of k-ras mutations in the pancreatic juice.
PubMedID- 25848351 A prediction rule was developed to stratify the risk for pancreatic cancer in patients with chronic pancreatitis, where gender, mass location, mass number, direct bilirubin, and ca 19-9 were included in the calculation .
PubMedID- 22617158 In several small hospital-based case–control studies, crp levels were significantly higher in pancreatic cancer cases compared with chronic pancreatitis patients or controls (barber et al, 1999; moses et al, 2009; mroczko et al, 2010).
PubMedID- 20065943 Little is known about the mechanism by which cigarette smoke or snus increase the risk of pancreatic cancer in individuals with chronic pancreatitis.
PubMedID- 24474940 Of the patients who progress to chronic pancreatitis, the risk of developing pancreatic cancer by age 70 years is approximately 40%.
PubMedID- 21114434 Conclusions: the prediction rule can provide available risk stratification for pancreatic cancer in chronic pancreatitis patients with focal mass lesions with prior negative eus-fna cytology.
PubMedID- 25789097 chronic pancreatitis increases the risk of developing pancreatic cancer.
PubMedID- 22022519 More recently, erkan et al used transcript profiling to identify markers to differentiate pasc’s associated with chronic pancreatitis versus those of pancreatic cancer, with the aim of subtyping pasc's into either inflammation or cancer-associated.
PubMedID- 23018013 The association of chronic pancreatitis with pancreatic cancer requires strict follow-up, especially in patients with inflammatory masses in the context of chronic pancreatitis.
PubMedID- 20103562 Of perhaps greatest concern in the case of the glp-1–based drugs, including glp-1 agonists and dipeptidyl peptidase-4 (dpp-4) inhibitors, is preliminary evidence to suggest the potential risks of asymptomatic chronic pancreatitis and, with time, pancreatic cancer.
PubMedID- 22414467 Among six genes, p16 was more specifically methylated in pancreatic cancer compared with chronic pancreatitis (p=0.016).
PubMedID- 20510834 pancreatic cancer in chronic pancreatitis; aetiology, incidence, and early detection.
PubMedID- 23060806 Using retrospective, histological examination of pancreases resected on suspicion of pancreatic cancer from patients with mass-forming chronic pancreatitis, american and european pathologists have described another unique histological pattern, called idiopathic duct-centric pancreatitis (idcp) (notohara et al., 2003), or aip with granulocytic epithelial lesion (gel) (zamboni et al., 2004).
PubMedID- 23053420 Gallstones, a cholecystectomy, chronic pancreatitis, and the risk of subsequent pancreatic cancer in diabetic patients: a population-based cohort study.
PubMedID- 23384807 This disruption can result from widespread pancreatic necrosis in acute pancreatitis, fibrotic replacement of the parenchyma as seen in chronic pancreatitis and in patients with pancreatic cancer where normal tissue is replaced by tumour and/or the pancreatic duct becomes obstructed.
PubMedID- 21661440 Incidence of and risk factors for developing pancreatic cancer in patients with chronic pancreatitis.
PubMedID- 22989892 The aim of this study was to confirm the high incidence of pancreatic cancer in patients with chronic pancreatitis in japan and to determine the factors associated with the risk for pancreatic cancer in patients with chronic pancreatitis.
PubMedID- 23296709 We also demonstrated upregulation of duox expression in vivo in pancreatic cancer xenografts and in patients with chronic pancreatitis.
PubMedID- 22057290 Chronic infection and subsequent inflammation are considered critical environmental and epigenetic factors contributing to tumor progression1, 2. primary examples are gastric cancer and helicobacter pylori infections, hepatocellular carcinoma and viral hepatitis, colitis-associated cancer, and pancreatic cancer associated with chronic pancreatitis1.
PubMedID- 22973234 Of particular relevance in this regard were the known increased risk of pancreatic cancer in patients with chronic pancreatitis (raimondi et al., 2010) and the commonalities in gene expression between the stromal compartments of chronic pancreatitis and pancreatic cancer (binkley et al., 2004).
PubMedID- 23531764 (2010) used transcript profiling to identify markers to differentiate psc associated with chronic pancreatitis against those of pancreatic cancer, with the ultimate aim of subtyping psc into either inflammation- or tumor-associated-psc.
PubMedID- 19854016 For eus, its diagnostic value decreased in differentiating pancreatic cancer for patients with chronic pancreatitis.
PubMedID- 23476808 Also risk of pancreatic cancer in chronic pancreatitis was dramatically increased with coexistence of diabetes (hr = 33.52), even though the role of dm may be overlooked in the presence of more acknowledged risk factors .
PubMedID- 25942306 pancreatic cancer in patients with recently diagnosed chronic pancreatitis.
PubMedID- 24660091 Smoking compounds can worsen chronic pancreatitis leading to pancreatic cancer .
PubMedID- 25937765 pancreatic cancer in chronic pancreatitis.
PubMedID- 24708788 Results: mif expression was significantly increased in pancreatic cancer tissues compared with chronic pancreatitis or normal pancreas specimens.
PubMedID- 23401773 Data were confirmed by high-density protein microarray in a large cohort of 140 patients affected by pancreatic cancer, 10 patients with chronic pancreatitis and 87 healthy controls.
PubMedID- 22511932 Given the fact that not all cases of pancreatic cancer are associated with chronic pancreatitis, it could be that other forms of inflammation have a similar effect.

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