PedAM
Pediatric Disease Annotations & Medicines
| Disease | pancreatic cancer |
| Symptom | C0011847|diabetes |
| Sentences | 59 |
| PubMedID- 21416850 | pancreatic cancer--association with diabetes mellitus and smoking. |
| PubMedID- 22084685 | diabetes mellitus is associated with pancreatic cancer in more than 80% of the cases. |
| PubMedID- 20178008 | Objective: the objective of this study was to test the association between calpain-10 (capn10), a diabetes susceptibility gene, with risk of pancreatic cancer (pc). |
| PubMedID- 25877316 | Analysis of the changes of blood glucose after radiotherapy in pancreatic cancer patients associated with diabetes mellitus and their related factors. |
| PubMedID- 22015968 | Objectives: type 2 diabetes is associated with increased pancreatic cancer risk; however, the nature of this relationship is not clear. |
| PubMedID- 24708788 | As shown in figure 5, the serum levels of mif in the following five group patients were examined: pancreatic cancer patients without diabetes, pancreatic patients with more than two years history of diabetes, pancreatic patients with less than two years history of diabetes (new-onset diabetes), healthy subjects with normal fasting glucose, and t2dm patients (without any other immune diseases or tumor) diagnosed within in two years. |
| PubMedID- 22920886 | An additional study in americans analyzed a total of 1,172,496 case and control subjects and found that the frequency of pancreatic cancer in subjects with diabetes was 0.9% in comparison to subjects without diabetes (0.3%) . |
| PubMedID- 26439801 | Thus, sod2/h2o2/mapk axis may represent a promising therapeutic target for pancreatic cancer patients combined with diabetes mellitus. |
| PubMedID- 23835106 | The significant, positive association remained after excluding pancreatic cancer cases with recent-onset diabetes (or=1.92; 95%ci: 1.20–3.08). |
| PubMedID- 21274445 | diabetes mellitus was associated with greater pancreatic cancer incidence , although there is limited data supporting the theory that sugars or sweets are pathogenetically implicated 7. |
| PubMedID- 23202913 | Obesity is being established as a risk factor for pancreatic cancer along with diabetes and decreased physical activity. |
| PubMedID- 23571023 | Studies have revealed that pancreatic cancer (pc) may lead to diabetes mellitus (dm). |
| PubMedID- 22982797 | pancreatic cancer patients with coexisting diabetes had better overall survival than pancreatic cancer patients without diabetes (hazard ratio, 0.60; 95% confidence interval 0.44 to 0.80; p<0.001). |
| PubMedID- 23399556 | Anti-diabetic medications and risk of pancreatic cancer in patients with diabetes mellitus: a systematic review and meta-analysis. |
| PubMedID- 22487526 | New-onset diabetes in pancreatic cancer: a study in the primary care setting. |
| PubMedID- 21412116 | Recent-onset diabetes associated with pancreatic cancer likely represents secondary or type 3 diabetes. |
| PubMedID- 22735942 | Risk factors and early signs of pancreatic cancer in diabetes: screening strategy based on diabetes onset age. |
| PubMedID- 22520674 | Risk factors examined included: age, body mass index, smoking status, alcohol, deprivation, diabetes, pancreatitis, previous diagnosis of cancer apart from pancreatic cancer, dysphagia, abdominal pain, abdominal distension, appetite loss, weight loss, diarrhoea, constipation, tiredness, itching, and anaemia. |
| PubMedID- 25673969 | We also compared the pancreatic cancer-only patients with the diabetes-only controls. |
| PubMedID- 25856529 | In addition, diabetes may be associated with pancreatic cancer risk or it may be an early indicator of disease . |
| PubMedID- 22792091 | pancreatic cancer patients with diabetes were predominantly females, while diabetes was equally prevalent among sexes in the control group. |
| PubMedID- 24224094 | Type 1 diabetes is associated with pancreatic cancer. |
| PubMedID- 24786605 | Our objective was to investigate the association of diabetes with survival among pancreatic cancer patients in a prospective cohort-based study where diabetes history was ascertained before pancreatic cancer diagnosis. |
| PubMedID- 21773024 | Some investigators would argue that diabetes is a result of pre-existing pancreatic cancer causing destruction of ß-cells via tumor infiltration . |
| PubMedID- 25275365 | We observed greater magnitude of hazard ratios (hrs) of pancreatic cancer for patients with type 2 diabetes along with acute alcoholic hepatitis, acute pancreatitis, cholecystitis, and gastric ulcer compared with patients without type 2 diabetes or counterpart comorbidity (hr: 1.36, 95% confidence interval (ci): 1.19-1.56; 1.74, 1.23-2.45; 9.18, 7.44-11.33; and 2.31, 1.98-2.70, respectively). |
| PubMedID- 19844672 | A possible underlying mechanism to account for an increased risk of pancreatic cancer in people with obesity and/or diabetes is chronically increased pancreatic duct cell replication. |
| PubMedID- 25806358 | Reports also indicate the association of diabetes with pancreatic cancer hence it is important to address the problem and to evaluate the relationship between them. |
| PubMedID- 26273663 | Tumor-derived peptide with an s-calcium binding protein is involved in the pancreatic cancer associated with diabetes which are the studies of bassoa and coworkers . |
| PubMedID- 25000673 | Information on the clinical profile of pancreatic cancer (pc) associated with diabetes mellitus (dm) is limited. |
| PubMedID- 26391180 | We also conducted a retrospective study in patients of pancreatic cancer with diabetes who underwent pancreatic cancer resection. |
| PubMedID- 24748867 | It is possible that new-onset diabetes associated with pancreatic cancer is due to a combination of beta cell dysfunction and an increased insulin resistance . |
| PubMedID- 25641178 | In addition, the serum levels of opg were significantly higher in pancreatic cancer patients with new-onset diabetes than other groups including pancreatic patients without diabetes, new-onset type 2 diabetes and healthy controls. |
| PubMedID- 22456038 | With long-standing type 2 diabetes, the risk of pancreatic cancer is increased by up to 50% (30,31). |
| PubMedID- 22960655 | Background & aims: new-onset diabetes in patients with pancreatic cancer is likely to be a paraneoplastic phenomenon caused by tumor-secreted products. |
| PubMedID- 25576058 | Metformin treatment is associated with a decreased risk and better prognosis of pancreatic cancer (pc) in patients with type 2 diabetes, but the mechanism of metformin's pc growth inhibition in the context of a prediabetic state is unknown. |
| PubMedID- 24574842 | Several studies have found an increased incidence of pancreatic cancer in patients with diabetes mellitus (dm); however, other studies have shown that pancreatic cancer may cause glucose intolerance. |
| PubMedID- 24058443 | The risk factors considered were smoking, heavy alcohol intake, high bmi, diabetes, family history of pancreatic cancer, abo non-o blood group and three common genetic variants identified by gwas. |
| PubMedID- 21067267 | Leptin and adiponectin in pancreatic cancer: connection with diabetes mellitus. |
| PubMedID- 25556126 | As pancreatic cancer induces diabetes in about 40% of patients,313233 we excluded retrospective and cross sectional studies to avoid reverse causality. |
| PubMedID- 23401773 | One hundred and twenty-six sera form pancreatic cancer patients (84 with diabetes) were examined by seldi-tof in comparison to 61 sera from chronic pancreatitis (32 with diabetes), 24 from type 2 diabetes mellitus patients, and 12 from healthy controls. |
| PubMedID- 24136929 | Genetic factors that modify the associations of obesity and diabetes with pancreatic cancer have previously not been examined at the genome-wide level. |
| PubMedID- 25061491 | The occurrence of pancreatic cancer is associated with diabetes and impaired glucose metabolism. |
| PubMedID- 24837144 | Metformin is associated with reduced risk of pancreatic cancer in patients with type 2 diabetes mellitus: a systematic review and meta-analysis. |
| PubMedID- 23383206 | In fact, diabetes increases the risk of developing pancreatic cancer ∼2-fold , . |
| PubMedID- 23400555 | However, diabetes as a result of pancreatic cancer development is not infrequent, and chronic pancreatitis explains only less than 3% of pancreatic cancer cases. |
| PubMedID- 23393682 | Damaged pancreatic tissue, secondary to pancreatic cancer, leads to diabetes as islet cells and beta cells are taken over by malignancy. |
| PubMedID- 20601806 | Clinical outcome of pancreatic cancer patients with diabetes mellitus: is diabetes a poor prognostic factor. |
| PubMedID- 23565475 | association of diabetes with pancreatic cancer is controversial with some studies, suggesting a two-fold increase in patients of diabetes of >5 years duration and others suggesting diabetes to be protective against pancreatic cancer. |
| PubMedID- 23669472 | Conclusions: diabetes is associated with pancreatic cancer risk and this is similar across different duration categories. |
| PubMedID- 26074965 | Similar survival benefits were seen in diabetes patients with pancreatic cancer on metformin . |
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