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PedAM

Pediatric Disease Annotations & Medicines




Disease pancreatic cancer
Symptom C0006625|cachexia
Sentences 13
PubMedID- 24404136 In pancreatic cancer patients with cachexia, no difference in the ratio of fast/slow myosin isoform was demonstrated compared with controls 6.
PubMedID- 22721276 Experimental design: we studied gene expression in skeletal muscle biopsies from pancreatic cancer patients with and without cachexia utilizing real-imaging cdna-aflp-based transcript profiling for genome-wide expression analysis.
PubMedID- 24624094 Over the last decade, we have gained new insight into the pathophysiology of cachexia associated with pancreatic cancer.
PubMedID- 25893413 Showed that pancreatic cancer patients with cachexia had a higher rate of more progressed tumor stages and a worse nutritional status.20 selection of patients with increased risk for poor postoperative outcome within this vulnerable group therefore is important.
PubMedID- 20590907 cachexia in pancreatic cancer: new treatment options and measures of success.
PubMedID- 22511317 Neural invasion induces cachexia via astrocytic activation of neural route in pancreatic cancer.
PubMedID- 23180446 Increased γ-aminobutyrate (gaba) levels were specific to cachexia in patients with pancreatic cancer.
PubMedID- 23051772 Increased gamma-aminobutyrate (gaba, p < 0.01) levels were specific to cachexia in patients with pancreatic cancer.
PubMedID- 21218002 barber et al., demonstrated that an epa-enriched supplement added to the diet may reverse cachexia in patients with advanced pancreatic cancer.
PubMedID- 24648112 pancreatic cancer-induced cachexia is jak2-dependent in mice.
PubMedID- 22473907 Crp was incorporated into a three-factor model of cachexia for patients with pancreatic cancer (fearon et al, 2006).
PubMedID- 26136412 In one of very few similar studies, schmitt et al.24 examined protein levels and phosphorylation status of muscle atrophy/hypertrophy pathway components in eight pancreatic cancer patients with cachexia compared with eight weight-stable cancer or pancreatitis patients.24 they observed reduced levels of akt, myhc, and foxo1 in the cachectic group.
PubMedID- 25341901 The highest rate of cachexia was 34.0%(89/262) in patients with pancreatic cancer followed by gastric cancer 22.4%(261/1164), colon cancer 21.7%(146/672), and rectal cancer 20.1%(117/581).

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