PedAM
Pediatric Disease Annotations & Medicines
| Disease | ovarian cancer |
| Symptom | C1608408|malignant transformation |
| Sentences | 4 |
| PubMedID- 26426652 | Dr. sampson in 1925 proposed a possible correlation between endometriosis and malignant transformation (occurrence of epithelial ovarian cancer eoc); thereafter, many epidemiologic studies, including recent systematic reviews1–9 and meta-analyses,3,4,10–12 indicated that women with endometriosis might have an increased risk of eoc. |
| PubMedID- 24279510 | However, it is unclear whether sphk1 is responsible for malignant transformation of ovarian cancer. |
| PubMedID- 21176222 | Significance: these observations suggest that reduced aldh1 expression is associated with malignant transformation in ovarian cancer and provides a basis for further study of the mechanism of aldh1 in this process. |
| PubMedID- 26078947 | Demonstrated that b7-h4 directly promoted malignant transformation of ovarian cancer cell line . |
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