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PedAM

Pediatric Disease Annotations & Medicines




Disease osteopetrosis
Symptom C0018952|extramedullary hematopoiesis
Sentences 2
PubMedID- 24708266 In summary, gross and histopathological lesions included long bone osteopetrosis with subsequent extramedullary hematopoiesis and lymphoid depletion.
PubMedID- 22351931 Interestingly, mice lacking ocl activity develop severe osteopetrosis, whch is associated with extramedullary hematopoiesis, suggesting that ocls may participate not only in the regulation or maintenance but also in the initial formation of the hsc niche (dougall et al., 1999; kong et al., 1999; tagaya et al., 2000; blin-wakkach et al., 2004b).

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