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PedAM

Pediatric Disease Annotations & Medicines




Disease neuropathy
Symptom C0002766|analgesia
Sentences 2
PubMedID- 22086103 It thus appears conceivable that the use of at least certain opioids in efforts to achieve analgesia in patients with painful hiv-related neuropathy may be less than ideal since at least certain opioid analgesics themselves may potentially contribute to "fueling the fire" of hiv enhanced pain hypersensitivity; at least in part via upregulation of specific chemokine receptors (e.g., cxcr4) which seem to be vitally important in promoting hiv-related pain facilitation.
PubMedID- 24278116 Future studies should elucidate other mechanisms of peripheral opioid analgesia in neuropathy (e.g.

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