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PedAM

Pediatric Disease Annotations & Medicines




Disease mental depression
Symptom C0085632|apathy
Sentences 26
PubMedID- 20658477 Although apathy is confused with depression, it might be a specific neuropsychiatric syndrome separate from depression.
PubMedID- 24624961 It has been previously concluded that depression can “lead to apathy in terms of self-care”.
PubMedID- 23372251 The index patient had resistant bipolar depression with significant apathy which improved significantly after modafinil was started.
PubMedID- 23351239 Caregiver burden and depression were associated with apathy rating discrepancies, while burden was associated with discrepancies in ratings of disinhibition.
PubMedID- 22760169 A comprehensive neuropsychiatric assessment focusing on the post-stroke hospitalization period showed severe motor, cognitive and affective apathy with no depression or other neuropsychiatric symptoms.
PubMedID- 21769255 It is well known that depression manifests with apathy, poverty of thought and lack of initiative, as observed in patients with long-standing adrenal insufficiency.
PubMedID- 24306058 apathy has been associated with depression, cognitive deficits, and poor quality of life.
PubMedID- 22166396 apathy coexisted with depression in 133 (36.9%) of pd patients, compared with depression without apathy in 16 (4.4%), apathy without depression in 84 (23%), and neither apathy nor depression in 127 pd patients (35.2%).
PubMedID- 21256069 Higher baseline depression was associated with higher baseline apathy, but not with change in apathy.
PubMedID- 20015839 apathy coexisted with depression in 43% of patients, compared with depression without apathy in 13% and apathy without depression in 17%.
PubMedID- 25273893 Objective: the aim of this study was to evaluate the predictive validity of the apathy subsyndrome in patients with therapy-resistant depression in the dose-remission study with transcranial pulsating electromagnetic fields (t-pemf).
PubMedID- 26090080 Indeed, in one study, half of the patients developed apathy associated with anxiety and depression on average 4 months after stn dbs when dopaminergic medications were markedly and abruptly decreased soon after surgery .
PubMedID- 22590475 Research in the area of dementia care covers a wide range of endpoints aiming at objectives as diverse as cognitive and linguistic capabilities, the capacity for remembering facts and things, agitation, social behavior, controlling aggressiveness or anxiety, overcoming apathy, dealing with depression (also by caregivers), coping with the mental burden in general, fitness for everyday life, and positively impacting the quality of life of patients and their caregivers.
PubMedID- 22693498 In one study on parkinson's patients , apathy coexisted with depression in 43% of the patients.
PubMedID- 23758953 depression with mental slowness, apathy or anxiety may mimic hydrocephalic symptoms and underlying depression is important to rule out or treat.
PubMedID- 23326757 As noted previously, a history needs to carefully distinguish what the patient means by their use of terms such as “fatigue,” “tiredness,” “exhaustion,” “drowsiness,” “lethargic,” and “groggy.” psychiatric conditions, such as depression with apathy and lack of motivation, can be misinterpreted as sleepiness .
PubMedID- 21437255 In addition, identifying apathy with depression may be one of the reasons for the poor response to anti-depressive treatment commonly seen in pd.
PubMedID- 22032742 Background: apathy is one hallmark of major depression (mdd).
PubMedID- 21655341 Elderly persons may be at greater risk than younger patients for comorbid conditions such as depression, which can lead to treatment apathy and reduced medication effectiveness.
PubMedID- 21747995 It seems likely that apathy in persons with depression results from alterations of the emotional and affective processing, but it may typically occur in the absence of a depressed mood (figure 1).
PubMedID- 21606898 Although a diagnosis of generalized anxiety disorder (gad) and apathy were also associated with the major depression cluster, irritability was not.
PubMedID- 22970412 The association of apathy with depression in pd is complex and there are studies which have shown a significant level of discrepancy between apathy and depression.
PubMedID- 24795586 Although apathy is part of symptoms of major depression, frequency, and intensity of apathy in hd patients increase with disease progression contrary to depression (kingma et al., 2008; van duijn et al., 2010).
PubMedID- 21895880 We related apathy with cognition (mmse), depression (montgomery asberg depression rating scale) and with outcome (modified rankin scale).
PubMedID- 21796258 apathy, one major determinant of geriatric depression, has been considered a major determinant of poorer outcomes in various clinical conditions;24,25 very recently, jorge et al26 reviewed the available evidence on the frequency, clinical correlates, mechanism, and treatment of apathy following stroke.
PubMedID- 23992241 apathy worsening was associated with pharmacological depression treatment in both unit types (p = 0.009; cohen's d, 0.35).

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