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PedAM

Pediatric Disease Annotations & Medicines




Disease male infertility
Symptom C0042341|varicocele
Sentences 14
PubMedID- 25967606 Methods: a total of 80 male infertility patients with varicocele were recruited from april 2011 to february 2012.
PubMedID- 24429393 A decreased ar expression and a consequent reduced responsiveness to dht in sperm may represent molecular mechanisms involved in the pathophysiology of varicocele leading to male infertility.
PubMedID- 20369544 Recent years have witnessed a lot of efforts devoted to the pathomechanism of varicocele-induced male infertility and rapid progress in researches on its cellular and molecular mechanisms, mainly including apoptotic abnormality and oxidative stress of germ cells.
PubMedID- 20495699 Therefore, studies on the association of a varicocele with male infertility are still needed to improve our understanding of the correlation between a varicocele and male infertility.
PubMedID- 25405715 varicocele is commonly associated with male infertility because it impairs normal sperm morphology and activity.
PubMedID- 23754533 Accumulating evidence suggests that varicocele, long associated with male infertility, is also a risk factor for low testosterone levels.
PubMedID- 22162682 A critical appraisal on the role of varicocele in male infertility.
PubMedID- 24236235 Hundred and six patients with varicocele associated with male infertility over a 5-year period were included into the study.
PubMedID- 22417329 Pathophysiology of varicocele in male infertility in the era of assisted reproductive technology.
PubMedID- 23227502 Aim: to improve the results of treatment for male infertility in patients with varicocele and to evaluate the efficiency of microsurgical varicocelectomy performed by the same surgeon in a large group of patients.
PubMedID- 25677140 Our previous study has shown a possible relationship between the gstt1 null genotype and the susceptibility to male infertility in patients with varicocele, and we found that the gstt1 positive genotype improved the antioxidant capacity, reduced the levels of ros in seminal plasma, and prevented injury caused by ros to the sperm dna in infertile patients with varicocele.8 a japanese group has reported that after varicocelectomy, the gstt1 positive genotype is associated with an improvement in the seminal findings of infertile patients with varicocele.9 in recent clinical practice, we have also found that patients with the gstt1 positive genotype have better responses to varicocelectomy than do patients with the gstt1 null genotype (data not shown).
PubMedID- 23582753 The present study identified prognostic factors for successful varicocelectomy for the treatment of varicocele-induced male infertility.
PubMedID- 22809864 varicocele, a cause of male infertility, occurs in nearly 40% of infertile males.
PubMedID- 23165400 varicocele, the leading cause of male infertility, can impair spermatogenesis through several pathophysiological mechanisms.

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