PedAM

Pediatric Disease Annotations & Medicines

Disease	malaria
Symptom	C0242723\|parasitemia
Sentences	38
PubMedID- 22144878	The bulk viscosity of blood in malaria increases with the parasitemia level due to the increased stiffness of pf-rbcs with respect to healthy rbcs.
PubMedID- 20949045	Few data are available on the prognostic significance of parasitemia in patients with severe imported malaria 3.
PubMedID- 24721983	The fixed value of 8,000 cells/μl to estimate parasitemia in malaria was arbitrarily chosen as the reference for the average number of leukocytes in a nigerian population in the 1950s 7.
PubMedID- 23091308	Therefore, flow cytometric examinations showed relatively higher parasitemia level of vivax malaria samples compared to microscopic observation, although statistical analysis was unavailable due to the limited number of experiments.
PubMedID- PMC4036668	These results imply that dosage regimens that result in immediate high blood concentrations of drug are those best able to reduce parasitemia in patients with evolving severe malaria and that sustained drug exposure achieved by sequential treatment with moderate doses offers no therapeutic advantage .
PubMedID- 22028888	Each erythrocytic cycle in a malaria patient with 1–10% parasitemia is believed to produce 0.2–2 g of hemozoin .
PubMedID- 21218028	Many parasitemia and clinical features of p. vivax malaria have been investigated so far, but most of the data have been acquired from tropical regions.
PubMedID- 24400637	Flt3 ligand treatment modulates parasitemia during infection with rodent malaria parasites via myd88- and ifn-gamma-dependent mechanisms.
PubMedID- 22305090	We examined health facility data for children seen as outpatients and parasitemia-positive children hospitalized with cerebral malaria in a large national hospital.
PubMedID- 23398940	Whether no controls, or not, acute parasitemia in malaria is unclear .
PubMedID- 23087389	Risk of severe knowlesi malaria increased 11-fold with parasitemia >20 000/microl, and 28-fold with parasitemia >100 000/microl.
PubMedID- 24902139	He was found to have a 1.5% parasitemia with malaria falciparum that borders on severe malaria.
PubMedID- 26471058	It leads to decreased parasitemia and resultant recovery of severe malaria by reducing parasite nutrient intake as well as by interfering with parasite metabolic machinery involved with iron .
PubMedID- 23724021	Cumulative incidence of first (or only) malaria infection with high parasitemia (≥5000 parasites/µl) and high parasitemia+fever were compared between bk-se36 and the control group.
PubMedID- 25759576	Once the malaria infection (parasitemia >5%) had been established in the mice, mtq and rtq were administered at four different concentrations (20 mg/kg, 10 mg/kg, 5 mg/kg, and 1 mg/kg).
PubMedID- 21760807	In cases of severe malaria with elevated parasitemia (>10% of red blood cells on a thin smear) that do not respond promptly to antimalarials, one may consider an exchange transfusion, although there is no strong clinical evidence to support its use .
PubMedID- 22114867	All malaria cases with parasitemia higher than 1000 parasites/μl were detected by optimal-it test (table 5).
PubMedID- 24642035	The role of submicroscopic parasitemia in malaria transmission: what is the evidence.
PubMedID- 24516592	More recently, it was shown that the presence of blood-stage parasitemia in malaria superinfection directly inhibits the development of subsequent liver stage infection as the result of increased production of iron-regulatory hormone hepcidin .
PubMedID- 23861883	Associations between antibodies and risk of symptomatic malaria (with parasitemia >2500/µl) were examined in children aged 1–10 years from the chonyi cohort.
PubMedID- 25147660	Although this patient received no medical treatment, the rapid and fatal course of malaria infection even with negative parasitemia in a nonimmune patient living in a nonendemic region, draws our attention to the importance of the relative immunity of people living in endemic regions (10).
PubMedID- 23136222	It differentiates severe malaria from thepopulation with asymptomatic parasitemia and the population with uncomplicated malaria,who have severe disease of a different origin.
PubMedID- 25476883	For example, there is a lack of sensitive and specific tests for the diagnosis of malaria cases with low parasitemia, and there is a need for surveillance tools that can evaluate the epidemic status for guiding the elimination strategy.
PubMedID- 21170302	T cells are thought to help control parasite numbers, but regulatory t cells, which are known to dampen immune responses, are present at a greater frequency in the blood of malaria patients with the highest parasitemia, suggesting that these cells might impair parasite control.
PubMedID- 26451382	At admittance to the hospital, falciparum malaria was diagnosed with parasitemia 7.4% and multiorgan failure.
PubMedID- 26053030	In the present study, we used a highly sensitive nested polymerase chain reaction (npcr) to determine whether subpatent parasitemia was a predictor of clinical malaria and if treatment with atazanavir was associated with lower rates of subpatent parasitemia or clinical disease in study participants recruited to a clinical trial of antiretroviral therapy that was conducted in malawi.
PubMedID- 26065879	Conclusion: c-reactive protein increases in malaria and correlates with parasitemia and some manifestations of complicated disease.
PubMedID- 22221310	This study was conducted to establish a cutoff point for peripheral parasitemia among patients with plasmodium falciparum malaria, to define severe malaria.
PubMedID- 23290088	Therefore, in addition to parasitemia, assessing severity of falciparum malaria using circulatory collapse and severe anemia will facilitate the diagnosis and management of malaria in ethiopia.
PubMedID- 26019283	Analyses were repeated using less strict definitions of malaria: without a minimum parasitemia threshold and also without a fever (but with the presence of malaria symptoms such as body aches, headache, or abdominal pain and treatment-seeking).
PubMedID- 26380342	At the end of the study, children in whom parasitemia was associated with febrile malaria were considered susceptible, whereas those who did not experience any febrile malaria despite parasitemia were considered protected.
PubMedID- 25973753	The usual low parasitemia present in settings of low malaria transmission will be better detected by more sensitive diagnostic tools.
PubMedID- 23372839	Because sensitivity of rdts is low when the parasite density <100/µl, the diagnosis of afebrile or atypical malaria with low parasitemia mainly depended on microscopy.
PubMedID- 24358031	Pregnant women are at comparatively high risk of p. falciparum, and possibly p. vivax, parasitemia in malaria endemic regions ,.
PubMedID- 21625634	In co-infected individuals, higher ifn-γ production could decrease parasitemia, leading to reduced malaria severity.
PubMedID- 20167126	Experimental infections of the rhesus macaque, m. mulatta, and the japanese macaque, m. fuscata, by p. coatneyi, p. knowlesi, p. cynomolgi or p. inui result in acute manifestations of malaria with high parasitemia, whereas these parasites produce less symptoms and low-grade infections in the long-tailed or crab eating macaque, m. fascicularis .
PubMedID- 26500831	Figure 4 shows the correspondence analysis result classified by the plasmodium species, parasitemia, and the number of previous malaria episodes.
PubMedID- 20967248	Although other more advanced methods based on flow cytometry or real-time pcr have been developed, the detection limit is only 0.003% for the flow cytometry measurement for parasitemia in malaria cultures with nuclear staining with yoyo-1 .

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