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PedAM

Pediatric Disease Annotations & Medicines




Disease malaria
Symptom C0036572|seizures
Sentences 15
PubMedID- 24080027 Nevertheless, it has been observed that this species can cause severe disease similar to plasmodium falciparum and complications caused by p. vivax mono-infection have been described, such as cerebral malaria with generalized seizures and epileptic status, severe anaemia, hepatic dysfunction and jaundice, acute lung lesion, acute respiratory distress syndrome (ards) and pulmonary oedema, shock, splenic rupture, acute renal failure and acute thrombocytopaenia with or without bleeding on different body sites .
PubMedID- 21482551 However, it is difficult to determine the proportion of seizures attributable to malaria in endemic areas since a significant proportion of asymptomatic children have malaria parasitaemia.
PubMedID- 23861864 Presumptive diagnosis of malaria, often associated with seizures, frequently caused delays in seeking appropriate care amongst our cases of abm at both household and health centre level.
PubMedID- 21816079 At the completion of these assessments, stratified randomisation for the three mni groups (cerebral malaria, malaria with seizures and malaria with impaired consciousness) to either the ccrt group (n = 28) or the non-treatment group (n = 33) was done (see figure 1).
PubMedID- 26444670 seizures due to malaria or bacterial meningitis.febrile seizures according to ilaeseizures associated with fever (temperature ≥38.5 °c) that occur in a sick child aged between a month to 6 years old, and the cause of fever does not involve the brain.febrile seizures according nihseizures with fever usually occurring in child aged between 3 months to 6 years in absence of neurological involvement.overall definition of febrile seizuresseizures with fever (temperature ≥38.5 °c) that occur in 2-8 % of children aged between 1 month to 6 years and exclude acute symptomatic seizures.definite prolonged seizuresseizures that last up to ≥10 minutes, and timing is witnessed by a clinician or nurse.probable prolonged seizuresseizures which did not stop after first dose of diazepam or continuing seizures that required second/third line antiepileptic drugs (phenobarbital/phenytoin).possible prolonged seizuresthese are prolonged seizures based on parental history i.e.
PubMedID- 24041795 We recently used a similar method to define and estimate the proportion of seizures attributable to falciparum malaria in a malaria-endemic area on the kenyan coast .
PubMedID- 21056005 Acute and serial eegs were especially important for identifying subclinical seizures, and inclusion of cerebral malaria retinopathy in the diagnostic criteria improved the certainty of diagnosis.
PubMedID- 23614351 Similarly, the association between icam1 polymorphisms seizures with severe malaria (kun et al., 1999) could be explained by the binding of icam1 to p. falciparum–infected erythrocytes onto brain microvasculature (berendt et al., 1992; kun et al., 1999) causing sequestration.
PubMedID- 22047193 Cerebral malaria, malaria with seizures and malaria with impaired consciousness, all shown to lead to cognitive deficits in african children, have been collectively termed 'malaria with neurological involvement' .
PubMedID- 22848783 Data on seven drug trials or combinations for preventing seizures associated with fever, alcohol, malaria, perinatal asphyxia, contrast media, tumors, craniotomy, and traumatic brain injury were evaluated.
PubMedID- 21103365 Findings from the iron supplementation study in tanzania that was terminated early because of increased all cause mortality and admissions to hospital , and the reduction in seizures in children with cerebral malaria after receiving an iron chelating agent as adjunct therapy suggest that translating the findings of the meta-analysis into a widespread iron supplementation as a preventive measure in the community would have to be undertaken with care.
PubMedID- 23853600 The appearance of neurological symptoms (shivering, tremors, ruffled fur, seizures, paralysis) associated with cerebral malaria (ecm) was monitored closely, and affected animals were immediately sacrificed as previously described .
PubMedID- 23383342 The index conditions for these 62 children were cerebral malaria, malaria with seizures, and malaria with impaired consciousness, with 9, 34, and 19 children in each index, respectively.
PubMedID- 25383238 For example, falciparum malaria is a cause of acute symptomatic seizures in children admitted to hospitals in sub-saharan africa, and these seizures are associated with neurological disabilities and epilepsy .
PubMedID- 25893405 Others thought malaria could lead to seizures (table 7).

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