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PedAM

Pediatric Disease Annotations & Medicines




Disease malaria
Symptom C0015967|fever
Sentences 120
PubMedID- 20727214 With only around a fifth of all fever episodes being associated with malaria parasitaemia, this review provides strong evidence to support the new who policy of laboratory-based diagnosis and treatment upon result .
PubMedID- 24596021 "comment: some of the authors are employed by the trial sponsors but all authors had access to data and assumed responsibility for reporting accuracy.ringwald 1996methodstrial design: randomized, parallel group, active controlled trialduration of trial: recruitment: april 1994 to may 1995participantsnumber randomized: 96age: 15 to 64 yearsgender: 42 males; 54 femalesinclusion criteria:acute falciparum malaria with fever within the past 24 hrs or a temperature above 37.5 °c at the time of consultationover 5000 asexual parasites/µlno signs and symptoms of severe and complicated malariano recent self-medicationexclusion criteria:pregnant womenmixed infectionsinterventionsintervention1.
PubMedID- 21304925 This threshold has previously been shown to be of value in differentiating symptomatic malaria from other causes of fever with coincidental parasitaemia .
PubMedID- 24279720 In zambia, for example, health workers diagnosed fewer than 30% of fever patients with a malaria rdt/blood slide following the introduction of a treatment protocol similar to that employed in png, even when rdts/microscopy were available 8.
PubMedID- 23922770 The probability of fever being due to malaria was assumed the same in the aggregated analysis but set to reflect the reduction in malaria incidence seen in tanzania.
PubMedID- 21499691 The rupture of the schizont and release of merozoites give rise to the so-called malaria paroxysms with spiking fever and rigors.
PubMedID- 21687657 Adult patients presenting in kapit district, malaysian borneo with fever and suspected of having malaria were recruited into this study between july 2006 and february 2009 and subsequently confirmed by pcr to carry single species plasmodium infections 3.
PubMedID- 21513544 In the coast region, tanzania, the powdered roots of c. mucronata are mixed with coconut oil for treatment of fresh wounds after extraction of jigger (tunga penetrans) while in other parts of tanzania, c. mucronata is used for treatment of indigestion, fever due to malaria and wounds .
PubMedID- 21080932 Multiple linear regression models with stepwise backward deletion were built to describe independent associations between covariates (fever, age and number of previous malaria episodes) and the presence of pmps.
PubMedID- 22846165 Children with symptoms and signs of malaria including: fever, chills, malaise, headache, vomiting or other systemic complaints were included in this study after informed consent was obtained from the parents/adolescent themselves.
PubMedID- 25588165 A multivariate regression model has been developed that utilized raman spectra of 20 malaria-infected, 10 non-malarial with fever, 10 healthy, and 6 dengue-infected samples to optically predict the malaria infection.
PubMedID- 20339579 A total of 18 health workers out of 25 (72%) confirmed that they prescribed treatment in the absence of laboratory diagnosis arguing that fever is strongly associated with malaria in an endemic area, and such an attitude allows to exclude for the patient thick and thin blood film cost which is officially charged 0.76 usd.
PubMedID- 23617626 Of the 55 positive rdt results withnegative blood smear, 31 (52%) were observed at inclusion but no detectablemicroscopic parasitaemia were identified, while 24 (48%) were observed laterduring the follow-up period but with no previously documented infection.peripheral malaria infection was associated with fever in only 16% of cases(n=62/361).
PubMedID- 23198986 Awareness by health professionals should increase so that any infant aged under 6 months brought to a health facility in a malaria-endemic area with unexplained fever or suspected sepsis should be systematically screened for malaria.
PubMedID- 26052704 malaria infection, fever and inflammatory syndrome in children at the time of hb measurement were significantly associated with a decrease in infant hb concentrations probably due to hemolytic anaemia.
PubMedID- 24722554 With growing awareness of the over-diagnosis and misclassification of malaria as the cause of fever illnesses in the tropics, including africa, there is increased interest in the role of non-malarial causes of fever, such as c. burnetii.
PubMedID- 21645402 Uncomplicated malaria generally presents with fever, malaise, and other non-specific symptoms; distinguishing malaria from other febrile illnesses based on clinical presentation is challenging .
PubMedID- 25312201 Results: the results showed that all the interviewees believed that children got malaria infection along with fever or fever and other symptoms.
PubMedID- 22035466 This can, for instance, be done through discussion platforms for clinicians about alternative management of fever with a negative malaria test.
PubMedID- 20877714 Few studies have evaluated the integrated management of fever due to pneumonia and malaria by chws in children ,, and the strategy of having chws dispense act has not been carefully evaluated.
PubMedID- 26186547 However, fever, in malaria endemic areas is the key symptom to offer malaria treatment 3.
PubMedID- 24415936 One child had symptomatic malaria (parasitemia with a fever requiring treatment) at the time of the blood draw, and 17 (22%) had blood smears demonstrating parasitemia.
PubMedID- 21599880 For this, clinical skills (but not necessarily physicians) are irreplaceable, in order to differentiate malaria from other causes of acute fever, such as benign viral infection or potentially dangerous conditions, which can all be present with the parasite co-existing only as a "commensal" or silent undesirable guest.
PubMedID- 23028559 In a study of the aetiology of fever amongst those with negative malaria rapid diagnostic tests, dengue and malaria were more frequent in the south and leptospirosis and typhoid more frequent in the north .
PubMedID- 24740584 Instead, the potential health benefits of introducing rdts are restricted to people whose fever is not due to malaria, for whom a negative rdt result should prompt the health worker to look for and treat the true cause of their fever.
PubMedID- 25649228 Two cross-sectional studies performed in cameroon in 2000 and 2004 indicate a slight reduction in the pediatric prevalence of asymptomatic carriage, but found no change in malaria prevalence in patients with fever .
PubMedID- 20624312 Presumptive treatment of fever with anti-malarials is widely practised to reduce malaria-attributable morbidity and mortality especially at lower level health facilities where microscopy is not readily available .
PubMedID- 23029433 Only 2% of fever cases were associated with malaria parasites in children <2 years during the act+llins period.
PubMedID- 22973831 During the last years, the prevalence of fever due to malaria has been drastically reduced in several countries including gabon.
PubMedID- 23977904 Seven (39%) health workers said patients do not trust rdt results and gave reasons, such as patients assuming that any fever is due to malaria (six), positive results reported at private health facilities (four) and suspecting they are tested for hiv (one).
PubMedID- 21939508 In this study among preschool children, it was aimed to assess effects of α+-thalassaemia on rates of fevers due to malaria and fever due to other causes, and evaluated to what extent these effects depended on age.
PubMedID- 26190968 Therefore, malaria induced fever and initial seizure episodes (mainly febrile) can contribute to heightened production of ammonia in the brain.
PubMedID- 23651521 Only 33% of fever patients were diagnosed with malaria using malaria rapid diagnostic tests (rdt) from this district’s health facilities .
PubMedID- 23936018 Having a fever (≥37.5°c) was predictive of having clinical malaria (or = 1.64, p value 0.011).
PubMedID- 22589226 As the rdt represents a cost in addition to the cost of medication, it may be perceived as unaffordable if the customer believes that the fever is probably due to malaria or that the best way to diagnose a disease is by trying different drugs until one of these removes symptoms (chandler et al.
PubMedID- 25584420 Majority of the women (84.98%) associated fever with malaria, while 44.17% associated it with chilling.
PubMedID- 20609211 The positive predictive value (ppv) for malaria infection in patients with fever was 72% (95% ci: 63-79) in the dry season and 88% (95% ci: 85-91) in the rainy season; the negative predictive value (npv) was 95% (95% ci: 92-97) and 88% (95% ci: 83-92) in the dry and rainy season, respectively.
PubMedID- 24009783 As part of a study investigating the aetiology of fever among patients with negative malaria tests, we recruited patients at salavan provincial hospital, salavan province, southern laos 3.
PubMedID- 21740570 The study considered patients at least two years old suffering from acute, uncomplicated plasmodium falciparum malaria with fever (axillary temperature ≥37.5°c) and a parasitaemia of between 1,000 and 100,000 trophozoites/μl in senegal and 2,000 to 200,000 trophozoites/μl in cameroon and ivory coast.
PubMedID- 20433718 In adult patients in this setting with fever or history of fever, those with malaria parasitaemia are more likely to have anaemia and malaria parasitaemia has a great public health impact on anaemia.
PubMedID- 24626194 For decades, a high importance was given to malaria as a cause of fever, which has led to an overestimation of its burden and at the same time an underestimation of other diseases.
PubMedID- 22952642 Since 2007, testing is recommended only for fever cases with malaria-related history and symptoms - body aches, joint pain, headache, nausea, vomiting, or diarrhea.
PubMedID- 22815732 Sepsis was defined as severe non-malaria febrile illness with fever, signs of shock including hypotension, tachypnoea or anuria these deaths could be further subdivided into confirmed infection with localizing signs or no localizing signs.
PubMedID- 23217163 In tropical africa, the differentiation of malaria from other causes of fever in the absence of microscopy is notoriously difficult.
PubMedID- 23320064 Estimated proportion of fever attributable to malaria parasitaemia varied substantially by malaria case definition and were nearly two fold greater in the high relative to low transmission season.
PubMedID- 21575152 Results of multivariate regression analysis of the association of fever with malaria when controlled for gender, age, residence, use of insecticide treated nets (itn) and wealth quintile.
PubMedID- 26390866 Also, fever in malaria is thought to be caused partly by tnf and other pyrogenic cytokines released as part of the human immune response to products of schizont rupture .
PubMedID- 21914203 This is to say that parasitological diagnosis of malaria in patients with fever or history of fever remains important in malaria endemic areas.
PubMedID- 23941585 Written consent was obtained from all participating volunteers, who were vaccinated against yellow fever and provided with malaria prevention and curative treatments according to world health organization (who) recommended regimen (on the basis of fever and detectable p. falciparum parasitemia).
PubMedID- 24475198 Each child was visited twice weekly; tympanic temperature was measured, and if the child had a fever or history of fever, a malaria rapid diagnostic test was performed and a blood smear collected.

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