PedAM
Pediatric Disease Annotations & Medicines
| Disease | lymphoma |
| Symptom | C0520743|mediastinal lymphadenopathy |
| Sentences | 5 |
| PubMedID- 25321448 | Endosonography for the diagnosis of malignant lymphoma presenting with mediastinal lymphadenopathy. |
| PubMedID- 21629192 | Diagnostic problems may arise when lymphoma manifests with primary mediastinal lymphadenopathy or a focal mass 7. |
| PubMedID- 20054702 | Synchronous mediastinal lymphadenopathy suggestive of non-hodgkin's lymphoma (nhl) or sarcoidosis was noted. |
| PubMedID- 24949340 | One study that included 156 patients with non-small-cell lung cancer undergoing ebus-tbna confirmed that epidermal growth factor receptor (egfr) mutations, k-ras mutations and p53 mutations can be analyzed in ebus-tbna samples, thus influencing therapeutic regimen and patients’ outcome.31 however, the literature related to the utility of fna in lymphoproliferative disorders remains controversial.3233 one recently retrospective study confirmed that ebus-tbna combined with rapid-on-site-evaluation (rose) provides sufficient samples for diagnosis and classification of malignant lymphoma in patients with mediastinal lymphadenopathy.33 thereby, an appropriate smear with an adequate amount of cells seems to be a crucial prerequisite for diagnosing and classification.3334 for further improvement of the amount and thus the quality of the samples, the transbronchial needle forceps (transbronchial needle biopsy, tbnb) was developed, to increase the quantity of the obtained material by ebus-tbna that provides comprehensive histological examination, immunohistochemistry and mutational analysis. |
| PubMedID- 26090115 | However, the diagnostic accuracy of ebus-tbna for the diagnosis of lymphoma in patients with mediastinal lymphadenopathy is not well defined. |
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