PedAM
Pediatric Disease Annotations & Medicines
| Disease | lymphocytic choriomeningitis |
| Symptom | C0009450|infection |
| Sentences | 84 |
| PubMedID- 25593185 | We evaluated whether induction of virus-specific cd4 t cells by vaccination would protect mice against infection with chronic lymphocytic choriomeningitis virus (lcmv). |
| PubMedID- 24711580 | We demonstrate that the potent antiviral type i interferons (ifns) directly inhibit co-stimulation-dependent t reg cell activation and proliferation, both in vitro and in vivo during acute infection with lymphocytic choriomeningitis virus (lcmv). |
| PubMedID- 23536658 | Given the practical implications of this claim, we decided to analyze in detail the quality of ad-primed cd8 t cells by directly comparing these cells to cd8 t cells induced through infection with lymphocytic choriomeningitis virus (lcmv). |
| PubMedID- 24531538 | Although irf4(-/-) cd8(+) t cells were initially capable of proliferation, irf4 deficiency resulted in limited cd8(+) t-cell responses after infection with the lymphocytic choriomeningitis virus. |
| PubMedID- 26363051 | Using a murine model of in utero hematopoietic cellular transplantation, the impact of an infection with lymphocytic choriomeningitis virus on prenatal allospecific tolerance was examined. |
| PubMedID- 21966366 | Similarly, after infection with lymphocytic choriomeningitis virus (lcmv) in mice, the adaptive immune response causes liver cell damage, choriomeningitis and destruction of lymphoid organ architecture. |
| PubMedID- 24928986 | To determine the significance of this finding, a week of b cell depletion in 4-mo-old mice was followed by acute viral infection with lymphocytic choriomeningitis virus armstrong. |
| PubMedID- 23580062 | Some important work has been done to describe the cellular dynamics of memory in response to infection with lymphocytic choriomeningitis virus (lcmv), but these studies did not consider their effects during long-term persistent infections , . |
| PubMedID- 20798510 | This review discusses the similarities and differences between infection with lymphocytic choriomeningitis virus (lcmv) in mice and chronic infection with hepatitis virus in humans. |
| PubMedID- 26147684 | We found that interleukin 10 (il-10) derived from cd4(+) regulatory t cells (treg cells) was necessary for the maturation of memory cd8(+) t cells following acute infection with lymphocytic choriomeningitis virus (lcmv). |
| PubMedID- 20079668 | Here we show that infection with th1 cell-promoting lymphocytic choriomeningitis virus (lcmv) reprogrammed otherwise stably committed gata-3(+) th2 cells to adopt a gata-3(+)t-bet(+) and interleukin-4(+)interferon-gamma(+) "th2+1" phenotype that was maintained in vivo for months. |
| PubMedID- 21964609 | Furthermore, similar to our previous published results showing impaired splenic memory generation by δe8i cd8αβ+t cells in response to intraperitonelial infection with lymphocytic choriomeningitis virus (lcmv)12, δe8i ot-i cd8αβ+ donor cells primed in vivo with lm-ova via the oral route, also failed to generate detectable memory cells in the spleen or the intestine of wild-type recipient mice (fig. |
| PubMedID- 20369005 | In the periphery mature naïve t cells deficient in dg showed both normal proliferation in response to allogeneic cells and normal migration, effector and memory t cell function when tested in acute infection of mice with either lymphocytic choriomeningitis virus (lcmv) or influenza virus. |
| PubMedID- 25127860 | Because canonical wnt (wingless/int1) signals critically regulate renewal versus differentiation of adult stem cells, we evaluated wnt signal transduction in cd8 t cells during an immune response to acute infection with lymphocytic choriomeningitis virus. |
| PubMedID- 19774496 | We report that infection of rats with lymphocytic choriomeningitis virus on postnatal day 4 induces il-1beta protein in select regions of the hippocampus on 6, 15, 21, and 45 days after infection. |
| PubMedID- 24141387 | This was first demonstrated following the infection of mice with lymphocytic choriomeningitis virus (lcmv) and listeria monocytogenes15,16. |
| PubMedID- 23566283 | During infection with lymphocytic choriomeningitis virus (lcmv) clone 13, the cd4(+) t-cell responses are lost. |
| PubMedID- 22355453 | In the developed world, infection with lymphocytic choriomeningitis virus (lcmv), an ow arenavirus associated with neurological and congenital disease, has been reported in organ transplant recipients and immunocompromised patients . |
| PubMedID- 24162775 | Klf2gfp p14 cd8+ t cells were adoptively transferred and primed by infection with lymphocytic choriomeningitis virus (lcmv) armstrong strain, and normal klf2gfp transgenic animals were infected with lcmv in parallel. |
| PubMedID- 23840678 | Following infection with lymphocytic choriomeningitis virus (lcmv), small numbers of adoptively transferred smarta tcr transgenic t cells, which are specific for a lcmv glycoprotein epitope (gp61–80), responded in a manner that mirrored the functionality, kinetics, effector differentiation, and memory development of polyclonal endogenous cd4+ responders to the same peptide in the same host. |
| PubMedID- 24158954 | In contrast, there is a negative effect of ifn-i on host resistance during chronic infection with lymphocytic choriomeningitis virus (lcmv) and acute infections with intracellular bacteria. |
| PubMedID- 23348876 | The immune-regulatory cytokine il-10 promotes chronicity of infection with lymphocytic choriomeningitis virus (lcmv) clone 13, as absence of il-10 or blocking of il-10r during early lcmv clone 13 infection results in viral clearance. |
| PubMedID- 25883318 | Using forward genetics in mice, we identified an orphan protein named lymphocyte expansion molecule (lem) that promoted antigen-dependent cd8(+) t cell proliferation, effector function, and memory cell generation in response to infection with lymphocytic choriomeningitis virus. |
| PubMedID- 25590581 | Here we show that during a persistent infection with lymphocytic choriomeningitis virus (lcmv) clone 13, mice lacking the glucocorticoid-induced tumor necrosis factor receptor related protein (gitr) exhibit defective cd8 t cell accumulation, increased t cell exhaustion and impaired viral control. |
| PubMedID- 22533989 | Although ccr7-deficient mice displayed reduced t-cell priming after infection with lymphocytic choriomeningitis virus or listeria monocytogenes, mice were able to generate sufficient immune responses . |
| PubMedID- 24590765 | We show here that b lymphocyte–induced maturation protein 1 (blimp-1)–deficient cd8 t cells fail to repress pd-1 during the early stages of cd8 t cell differentiation after acute infection with lymphocytic choriomeningitis virus (lcmv) strain armstrong. |
| PubMedID- 22745374 | Spi2a was also required for the maintenance of central memory cd8(+) t cell populations after acute infection with lymphocytic choriomeningitis virus. |
| PubMedID- 25253351 | infection with either lymphocytic choriomeningitis virus (lcmv) or yellow fever virus (yf) results in gradual upregulation of socs1/3 mrna expression peaking at day 7 postinfection (p.i.). |
| PubMedID- 25987506 | Added to this, iel expand after systemic infection with lymphocytic choriomeningitis virus19 and during oral infection by reovirus and rotavirus2021. |
| PubMedID- 22916013 | After infection with lymphocytic choriomeningitis virus (lcmv) or vaccinia virus, specific antiviral t cell responses were significantly reduced in old, old mcmv-infected and/or tx mice compared to young mice. |
| PubMedID- 25934860 | In this study, we compared the phenotype and function of treg cells during acute or chronic infection with lymphocytic choriomeningitis virus. |
| PubMedID- 21878672 | Although both strains lacked nk-cell cytotoxicity, only souris mice developed all clinical and histopathologic signs of hlh after infection with lymphocytic choriomeningitis virus. |
| PubMedID- 26101541 | For instance, pml−/− mice exhibit increased viral load after infection with lymphocytic choriomeningitis virus (lcmv) and vesicular stomatitis virus (vsv) . |
| PubMedID- 25709608 | More recently, was−/− mice were shown to be unable to clear an infection with the lymphocytic choriomeningitis virus (lcmv) and to declare increased immunopathology (93). |
| PubMedID- 26029211 | A phenomenon observed for some microbes, including systemic infection with lymphocytic choriomeningitis virus (lcmv) (93) and l. monocytogenes (94, 95), is partial or complete inkt cell depletion, which may last for several weeks. |
| PubMedID- 21830209 | Using cd8(+) t cells deficient for il-12 or type i ifn receptors in an adoptive transfer system, we generated memory populations after infection with vaccinia virus, lymphocytic choriomeningitis virus or listeria monocytogenes. |
| PubMedID- 22241999 | Most likely, this is because unlike other frequently used models such as intraperitoneal infection with lymphocytic choriomeningitis virus (lcmv, figure 1c, clear circles) there is no systemic t1-ifn activity during early ectv infection. |
| PubMedID- 20585572 | We show that requirement for cellular pkr activity could be a distinguishing feature between type i ifn actions that mediate viral control or stimulate cd8+ t cell expansion during an acute infection with lymphocytic choriomeningitis virus (lcmv). |
| PubMedID- 24647402 | infection with lymphocytic choriomeningitis virus (lcmv) was suspected. |
| PubMedID- 23403622 | After infection with lymphocytic choriomeningitis virus, pearl mice developed all key features of hlh, linked to impaired virus control caused by a moderate defect in ctl cytotoxicity in vivo. |
| PubMedID- 24760883 | Following systemic infection with lymphocytic choriomeningitis virus (lcmv), stat1 knockout (ko) mice but not wild-type, stat2 ko, irf9 ko, or ifnar ko mice develop lethal disease perpetrated by cd4(+) t cells. |
| PubMedID- 24631156 | Stat3-deficient cd4(+) t cells had a profound defect in tfh cell differentiation, accompanied by decreased germinal center (gc) b cells and antigen-specific antibody production during acute infection with lymphocytic choriomeningitis virus. |
| PubMedID- 20185585 | After infection with lymphocytic choriomeningitis virus, we observed a substantial, lymphotoxin (lt) beta-receptor-dependent reorganization of the pln microarchitecture, in which an initial b-cell influx was followed by 3-fold increases in pln volume and hev network length on day 8 after infection. |
| PubMedID- 20442876 | Similarly, the induction and expansion of cd8+ t cells during infection with lymphocytic choriomeningitis virus (lcmv) depended on c3 . |
| PubMedID- 21832162 | In contrast, cd4(+) or cd8(+) t cells do not produce il-17a in response to acute or protracted viral infection with lymphocytic choriomeningitis virus or during autoimmune diabetes development in the cd8-driven lymphocytic choriomeningitis virus-induced model of type 1 diabetes. |
| PubMedID- 23650439 | Although the frequency of cd127+ nk cells was reduced on day 6 of infection with lymphocytic choriomeningitis virus (lcmv) strain armstrong (acute infection), it was increased on day 21 of infection with the chronically persisting lcmv clone 13 (fig. |
| PubMedID- 25362489 | We report here that autophagy was dynamically regulated in virus-specific cd8(+) t cells during acute infection of mice with lymphocytic choriomeningitis virus. |
| PubMedID- 23984639 | Two reports have shown independently that this mirna is essential for cd8+ t cell responses upon infection with lymphocytic choriomeningitis virus (lcmv), where it appeared to influence t cell survival upon viral infection. |
| PubMedID- 22583867 | In contrast, antibody responses to infection with lymphocytic choriomeningitis virus, the virions of which contain less densely packed spikes, are t cell dependent . |
| PubMedID- 22117048 | infection with lymphocytic choriomeningitis virus induces monopoiesis in wild-type mice, but causes increased neutrophil production in ifngamma(-/-) mice. |
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