PedAM
Pediatric Disease Annotations & Medicines
| Disease | lyme disease |
| Symptom | C0009450|infection |
| Sentences | 19 |
| PubMedID- 23967405 | Discovery of the spirochetal aggrecanase raises many questions about the pathogenesis of lyme arthritis and lends support to the concept of persistent b. burgdorferi infection in patients with chronic lyme disease symptoms. |
| PubMedID- 23346260 | While secondary neuroborreliosis is believed to be an active and ongoing infection , the existence of chronic lyme disease induced by persistent b. burgdorferi infection is sharply debated. |
| PubMedID- 25671085 | Subsequent investigations revealed evidence of anti- borrelia seroactivity in eia-igg and igg-blot, suggesting a recent infection with lyme disease, and resulted in a 4-week treatment with oral doxycycline. |
| PubMedID- 26469785 | In support of the literature , the study suggests a high co-infection rate with either lyme disease or ehrlichiosis for recorded babesiosis cases. |
| PubMedID- 26430734 | A widely reported hypothesis for the variation in tick infection rates with the lyme disease pathogen (borrelia burgdorferi) is the “dilution effect”. |
| PubMedID- 23940747 | Murine infection with the lyme disease spirochete borrelia burgdorferi), innate immunity has been shown to be critical for limiting pathogen burdens , , . |
| PubMedID- 22590620 | Examining the ability to detect b. burgdorferi infection in patients with early lyme disease at the initial physician visit with either laboratory test, ia/pcr/esi-ms or two-tiered serology, resulted in 19 of 21 patient specimens (90% with a 95% confidence interval of 70% to 99%) having a positive detection of b. burgdorferi infection. |
| PubMedID- 26214509 | For example the only environmental parameter linked to an increased infection rate with tick-borne lyme disease in humans is the occurrence of woodland 6. |
| PubMedID- 26370123 | Severe symptomatic babesiosis co-infection with lyme disease. |
| PubMedID- 23042964 | Methods: blood culture and serology were used to detect hga infection in patients with early lyme disease who presented with erythema migrans. |
| PubMedID- 24950221 | Analysis of the transcriptome of borrelia burgdorferi, the causative agent of lyme disease, during infection has proven difficult due to the low spirochete loads in the mammalian tissues. |
| PubMedID- 25870274 | Hypercholesterolemia and apoe deficiency result in severe infection with lyme disease and relapsing-fever borrelia. |
| PubMedID- 24009501 | Analysis of the transcriptome of borrelia burgdorferi, the causative agent of lyme disease, during infection has proven difficult due to the low spirochete loads in the mammalian tissues. |
| PubMedID- 22524232 | Based on the observations of this study we propose that neurologic injury in the cns during an infection with the lyme disease spirochete b. burgdorferi could be mediated in part by the direct action of the spirochetes on oligodendrocytes or via inflammation mediated by b. burgdorferi in oligodendrocytes. |
| PubMedID- 22294245 | Lastly, a predictive relationship between the triggering event of infection with lyme disease and the onset of persistent symptoms cannot be established. |
| PubMedID- 22108011 | Burgdorferi infection prevalence, the risk of acquiring lyme disease appears to be low. |
| PubMedID- 23400696 | According to the laws of probability, a concurrent hga infection in patients with lyme disease might amount to a few percent at most. |
| PubMedID- 24416278 | Although human risk of infection with lyme disease was best predicted by a self-reported previous lyme disease diagnosis, we excluded this variable from further analyses to gain insights into specific behavioral and environmental risk factors. |
| PubMedID- 25517089 | Sensitization resulted in a cytokine skew favoring a th2 bias as well as partial (57%) protection to infection with lyme disease spirochetes (borrelia burgdorferi) following infected tick challenge when compared to tick naive counterparts. |
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