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PedAM

Pediatric Disease Annotations & Medicines




Disease lupus erythematosus
Symptom C0272242|complement deficiency
Sentences 2
PubMedID- 24428878 They included use of any investigational drug within 30 days prior to study commencement or during the study; patients with a known complement deficiency associated with systemic lupus erythematosus, paroxysmal nocturnal hemoglobinuria, hereditary angioedema, membranoproliferative glomerulonephritis, collagen vascular disease, autoimmune hepatitis, primary biliary cirrhosis, scleroderma, or recurrent neisserial infections; or patients with confirmed hiv infection.
PubMedID- 22129056 Specifically, we discuss a group of conditions, including aicardi-goutieres syndrome, spondyloenchondrodysplasia, and cases of systemic lupus erythematosus with complement deficiency, in which an upregulation of type i interferons is apparently central to their pathogenesis.

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