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PedAM

Pediatric Disease Annotations & Medicines




Disease lupus erythematosus, systemic
Symptom C0055781|circulating anticoagulants
Sentences 2
PubMedID- 22473619 These assays have their origins beginning >60 years ago, with the identification of the biologic false positive test for syphilis, the observation of "circulating anticoagulants" in certain patients with systemic lupus erythematosus, the identification of cardiolipin as a key component in the serologic test for syphilis, and the recognition and characterization of a "cofactor" for antibody binding to phospholipids.
PubMedID- 22259629 Conley and hartman in 1972 to describe antibodies that inhibited pl-d coagulation in vitro.

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