PedAM
Pediatric Disease Annotations & Medicines
| Disease | lung cancer |
| Symptom | C0220650|brain metastases |
| Sentences | 91 |
| PubMedID- 20335119 | Objective: to establish a diagnostic model of protein fingerprint pattern in the cerebrospinal fluid (csf) for non-small-cell lung cancer (nsclc) patients with brain metastases. |
| PubMedID- 26336472 | Results of surgical treatment of primary lung cancer with synchronous brain metastases. |
| PubMedID- 22678505 | A 74-year-old diabetic patient who had a history of non-small cell lung cancer with brain metastases and subsequent treatment with srs, presented with a focal lesion in the left centrum semiovale with progressively worsening edema. |
| PubMedID- 24019862 | The lung cancer patient lc1 with brain metastases had not been undergoing any treatment. |
| PubMedID- 21224697 | Two cases of lung cancer patients with postoperative brain metastases obtaining long-term survival after gamma knife radiosurgery. |
| PubMedID- 21735751 | Clinical diagnosis of primary lung cancer with multiple brain metastases was made, and he underwent whole brain radiotherapy. |
| PubMedID- 25247337 | Efficacy of the irreversible erbb family blocker afatinib in epidermal growth factor receptor (egfr) tyrosine kinase inhibitor (tki)-pretreated non-small-cell lung cancer patients with brain metastases or leptomeningeal disease. |
| PubMedID- 25031274 | Background: median survival of non-small cell lung cancer (nsclc) patients with brain metastases is poor. |
| PubMedID- 24852190 | Human herpesvirus 6 encephalitis simulating brain metastases in a patient with advanced small-cell lung cancer. |
| PubMedID- 22933980 | Outcome of small cell lung cancer (sclc) patients with brain metastases in a routine clinical setting. |
| PubMedID- 24606446 | Background: the incidence of brain metastases (bm) varies in patients with non-small cell lung cancer (nsclc), calls into question the value of prophylactic cranial irradiation (pci). |
| PubMedID- 23443093 | Recently established a spontaneous brain metastases model of lung cancer by surgical orthotopic implantation (soi) techenique, thus making it possible to mimic the initial process of malignancy metastasis. |
| PubMedID- 24649230 | The histological type of lung cancer in patients with brain metastases may affect response to treatment and survival. |
| PubMedID- 26553452 | Most lung cancer patients with brain metastases have multiple lesions, and this is associated with a survival time of 3–6 months. |
| PubMedID- 20728237 | Cisplatin, fotemustine and whole-brain radiotherapy in non-small cell lung cancer patients with asymptomatic brain metastases: a multicenter phase ii study of the gruppo oncologico italia meridionale (goim 2603). |
| PubMedID- 20636143 | Is "routine" cranial irradiation in hemiplegic lung cancer patients with brain metastases justified. |
| PubMedID- 20591632 | Aims: to study various prognostic factors affecting outcome and to validate radiation therapy oncology group recursive partitioning analysis (rpa) class in non-small cell lung cancer (nsclc) with brain metastases treated with short-course accelerated radiotherapy (scar). |
| PubMedID- 21772102 | A case of long-term remission of small-cell lung cancer with multiple brain metastases. |
| PubMedID- 26182869 | Methods: lung cancer cases with brain metastases were retrospectively collected during 2002 and 2008 from shanghai chest hospital, shanghai jiao tong university. |
| PubMedID- 24772316 | The available treatment options for lung cancer with brain metastases (bm) are currently limited. |
| PubMedID- 24197981 | Egfr mutation status and its impact on survival of chinese non-small cell lung cancer patients with brain metastases. |
| PubMedID- 21972711 | The role of surgical treatment of primary non-small cell lung cancer with synchronous brain metastases. |
| PubMedID- 22613338 | Background and objective: the aim of this study is to evaluate the efficacy of selected arterial infusion chemotherapy in treating non-small cell lung cancer (nsclc) with multiple brain metastases and corresponding factors to influencing prognosis. |
| PubMedID- 25628027 | Squamous cell histology was associated with worse prognosis after resection of brain metastases in patients with non-small cell lung cancer. |
| PubMedID- 24577133 | Background: survival upon diagnosis of brain metastases (bm) in patients with non-small cell lung cancer (nsclc) is highly variable and established prognostic scores do not include tissue-based parameters. |
| PubMedID- 22430135 | Cxcr4 and cxcl12 immunoreactivities differentiate primary non-small-cell lung cancer with or without brain metastases. |
| PubMedID- 21697413 | Conclusion: radiobiological models suggest that if there is a non-uniform distribution of microscopic brain metastases in patients with small cell lung cancer, higher population-based metastasis-free rates might be achievable with non-uniform irradiation compared with the same integral whole-brain dose delivered as a uniform prescription. |
| PubMedID- 24022905 | Long-lasting response to crizotinib in brain metastases due to eml4-alk-rearranged non-small-cell lung cancer. |
| PubMedID- 21766491 | Purpose: to evaluate the clinical and radiologic response rates, toxicity and tolerability of 2x8 gy whole brain radiotherapy (wbrt) in lung cancer patients with brain metastases (bm). |
| PubMedID- 23376611 | Bevacizumab is now allowed for non-small cell lung cancer (nsclc) patients with brain metastases and non-squamous histology. |
| PubMedID- 24904894 | Outcome of surgical resection of symptomatic cerebral lesions in non-small cell lung cancer patients with multiple brain metastases. |
| PubMedID- 23503999 | Though lung cancer with brain metastases is a possibility in patients presenting with chest tumor and altered mental states, solitary fibrous tumor (with hypoglycaemia) should also be considered. |
| PubMedID- 23110940 | Survival of non-small cell lung cancer patients with brain metastases treated with brain rt stratified by egfr mutation status. |
| PubMedID- 21792167 | Combined treatment of non-small cell lung cancer with synchronous brain metastases: a single center experience. |
| PubMedID- 25780337 | Several seminal papers convinced many leading researchers that cscs are real in human cancers, notably breast,2 ovarian,3 brain metastases of lung cancer,4 pancreatic cancer,5 and glioblastoma.6 now there is vigorous activity in identifying or developing agents specifically capable of killing or suppressing cscs and in moving these agents through the clinical trial system rapidly. |
| PubMedID- 25583566 | Egfr tyrosine kinase inhibitors versus cranial radiation therapy for egfr mutant non-small cell lung cancer with brain metastases: a systematic review and meta-analysis. |
| PubMedID- 23393579 | Primary tumor types vary in their propensity to form brain metastases (bm) with lung cancer, breast cancer and melanoma showing the highest incidences of central nervous system (cns) involvement. |
| PubMedID- 25656857 | Systemic treatment of lung cancer patients with brain metastases is based on clinical (presence of symptomatic intracranial lesions), pathological and molecular characteristics of the disease. |
| PubMedID- 26469914 | Depending on the results of clinical trials or case reports of the use of erlotinib and afatinib, afatinib plus brain radiotherapy or surgery may represent a reasonable choice in the treatment of egfr-mutated lung cancer with brain metastases. |
| PubMedID- 26218580 | Background: numerous studies have focused on the treatment of non-small cell lung cancer patients with brain metastases. |
| PubMedID- 25313746 | Fractionated stereotactic radiotherapy for small-cell lung cancer patients with brain metastases. |
| PubMedID- 21321089 | Pemetrexed and cisplatin as first-line chemotherapy for advanced non-small-cell lung cancer (nsclc) with asymptomatic inoperable brain metastases: a multicenter phase ii trial (gfpc 07-01). |
| PubMedID- 20395118 | The management of brain metastases in patients with non-small cell lung cancer-is it time to go back to the drawing board. |
| PubMedID- 26407999 | brain metastases arising from primary lung cancer contribute significantly to the morbidity and mortality of the disease. |
| PubMedID- 22780988 | Developed a prognostic index for patients with wbrt for brain metastases of lung cancer and scored the factors age, ecog performance status, histology, weight loss, primary and systemic disease status . |
| PubMedID- 25619758 | Cancers included rcc (n = 5), glioblastoma (n = 4), and non-small-cell lung cancer with brain metastases (n = 1). |
| PubMedID- 25842091 | Treatment and control of brain metastases are important in patients with non-small cell lung cancer (nsclc). |
| PubMedID- 20604919 | As a further support to this hypothesis, increased her3 expression has also been reported in brain metastases of lung cancer . |
| PubMedID- 20009927 | Multimodality management of non-small cell lung cancer patients with brain metastases. |
| PubMedID- 25925626 | Another trial84 examined the use of primary chemotherapy for newly diagnosed non-small cell lung cancer with synchronous brain metastases (with delayed wbrt at brain relapse) versus wbrt administered first. |
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