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PedAM

Pediatric Disease Annotations & Medicines




Disease lung cancer
Symptom C0037116|silicosis
Sentences 4
PubMedID- 25923988 Though the association of silicosis with lung cancer has been suspected for many decades, there were no established model systems to study mechanisms that link cs-induced chronic inflammation to lung cancer promotion.
PubMedID- 20660960 Detection of lung cancer in silicosis patients using a tumor-marker panel.
PubMedID- 26183169 However, silica is a well-known cause of pneumoconiosis, often presenting as chronic bronchitis, emphysema and lung fibrosis.20, 21 in addition, lung cancer has been associated with silicosis, which is induced by inhalation of silica.22 silicosis may cause various autoimmune disorders, including rheumatoid arthritis, systemic lupus erythematosus, systemic sclerosis and vasculitis.23, 24 due to these potential health risks, the use of silica should be carefully regulated and handled with proper safety precautions.
PubMedID- 23112505 much work has been done on the association of silicosis with lung cancer and it was found that ultrafine silicon dioxide is cytotoxic and genotoxic in cultured human cells, while yang et al.

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