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PedAM

Pediatric Disease Annotations & Medicines




Disease liver disease
Symptom C0282193|iron overload
Sentences 13
PubMedID- 24662623 Estimating iron overload in patients with suspected liver disease and elevated serum ferritin.
PubMedID- 21417913 Background: research suggests the presence of mild-to-moderate iron overload in patients with nonalcoholic fatty liver disease (nafld).
PubMedID- 25647178 Increased levels of tfr-1 have previously been reported in alcoholic liver disease in correlation with hepatocellular iron overload, and ascribed to stabilization of irps following hepatic oxidative stress .
PubMedID- 24021424 We identify nrf2 as a potential modifier of liver disease in iron overload pathology and show the beneficial effect of the antioxidant mito-tempol in a mouse model of dietary iron-induced liver injury.
PubMedID- 23776499 But only eng and his colleagues reported excessive brain iron accumulation in three patients with hepatic iron overload, due to end-stage liver disease .
PubMedID- 19925473 Hepatic and cardiac iron overload among patients with end-stage liver disease referred for liver transplantation.
PubMedID- 24816174 While the association between iron overload and development of end-stage liver disease is well established, the underlying mechanisms are largely unknown.
PubMedID- 24926259 The use of phlebotomy is relatively common for 'difficult-to-treat by antiviral therapies' hepatitis c virus (hcv)-infected patients and for certain patients having chronic liver diseases with an iron overload of the liver.
PubMedID- 20490691 Effect of epigallocatechin-3-gallate on iron overload in mice with alcoholic liver disease.
PubMedID- 23749468 The liver is the central regulator of iron metabolism and accordingly, chronic liver diseases often lead to systemic iron overload due to diminished expression of the iron-regulatory hormone hepcidin.
PubMedID- 21747885 The reason for this is not clear but might be explained by liver disease associated with transfusion-related iron overload, the presence of undiagnosed ttv genotypes, or other blood-borne agents.
PubMedID- 23657305 Hfe mutations and iron overload in patients with alcoholic liver disease.
PubMedID- 25079484 Objectives: neonatal haemochromatosis is a rare gestational disease that results in severe foetal liver disease with extrahepatic iron overload, sparing the reticuloendothelial system.

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