PedAM
Pediatric Disease Annotations & Medicines
| Disease | liver disease |
| Symptom | C0040034|thrombocytopenia |
| Sentences | 22 |
| PubMedID- 24686514 | These agents are currently in development for the treatment of thrombocytopenia in patients with chronic liver disease and liver cirrhosis . |
| PubMedID- 26573200 | A case report of immune thrombocytopenia with drug induced liver disease. |
| PubMedID- 26501978 | Currently, two global phase iii trials are ongoing evaluating the efficacy and safety of once-daily oral avatrombopag for the treatment of adults with thrombocytopenia associated with liver disease prior to an elective procedure (clinical trial no: nct01972529 and nct01976104). |
| PubMedID- 24714308 | No correlation between the size of the spleen and the amount of platelet specific immunoglobulin was found, and this may partly explain the inconstant relationship between the size of the spleen and the degree of thrombocytopenia in patients with chronic liver disease 9. |
| PubMedID- 21131941 | thrombocytopenia associated with chronic liver disease: effects of rifaximin on platelet count. |
| PubMedID- 24100055 | Background: thrombocytopenia in patients with end-stage liver disease is a common disorder caused mainly by portal hypertension, low levels of thrombopoetin, and endotoxemia. |
| PubMedID- 24696622 | Similarly, chronic liver disease patients with thrombocytopenia who need to undergo an invasive procedure may be potential candidates for short two-week courses of eltrombopag in the periprocedural period to help reduce the risk of bleeding. |
| PubMedID- 20565378 | Despite prolonged coagulation times and thrombocytopenia associated with end-stage liver disease, formation of thrombi in the circulation seems to occur more frequently during liver transplant than during any other type of major surgery. |
| PubMedID- 25222481 | The present review focuses on the etiologies and management options for severe thrombocytopenia in the setting of advanced liver disease. |
| PubMedID- 20919743 | Given the fact that thrombocytopenia is associated with chronic liver diseases, and the multifunctional nature of platelets we reason that phenotype-specific platelets could be the systemic barometer for hepato-carcinogenesis. |
| PubMedID- 26191473 | We regarded a patient to have liver injury based on the following clinical data: (1) elevation of serum aspartate aminotransferase (ast) and/or alanine aminotransferase (alt) levels, or (2) the existence of primary liver disease associated with thrombocytopenia with platelet counts below 100,000/μl. |
| PubMedID- 22257364 | Eltrombopag is not yet licensed for treatment of thrombocytopenia in patients with chronic liver disease because the risk of portal venous thrombosis (pvt) increased substantially when this drug was administered at 75 mg daily for 14 days . |
| PubMedID- 20443100 | Conclusions: our data suggest that partial splenic arterial embolization leads to an increase in platelet count in patients with thrombocytopenia due to chronic liver disease and hypersplenism. |
| PubMedID- 21637276 | Small intestinal bacterial overgrowth and helicobacter pylori: can they be cause of thrombocytopenia in patients with chronic liver disease. |
| PubMedID- 24478597 | It is stillcontroversial whether the thrombocytopenia observed in patients with chronic liver diseaseis more associated to splenomegaly or to very high portal blood pressure. |
| PubMedID- 23339384 | Correcting thrombocytopenia in patients with liver diseases: a difficult hurdle. |
| PubMedID- 23086124 | thrombocytopenia in patients with chronic liver disease: what's in a name. |
| PubMedID- 24356057 | Deterioration was associated with drooling, leukopenia, thrombocytopenia, splenomegaly and evidence of chronic liver disease. |
| PubMedID- 26459859 | Overall the current study gives a better understanding of a novel approach to deal with thrombocytopenia associated with liver diseases with elevated ucb. |
| PubMedID- 20182351 | Variables including acidosis, hypothermia, hypofibrinogenaemia, thrombocytopenia and model of end-stage liver disease (meld) score were not associated with clinical response to rfviia. |
| PubMedID- 22054278 | Romiplostim in chronic liver disease with severe thrombocytopenia undergoing an elective invasive procedure. |
| PubMedID- 22674141 | We evaluated the pharmacokinetics, efficacy, and safety of eltrombopag in japanese patients with thrombocytopenia associated with chronic liver disease (cld). |
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