PedAM

Pediatric Disease Annotations & Medicines

Disease	liver disease
Symptom	C0005779\|coagulopathy
Sentences	21
PubMedID- 24999219	coagulopathy is common in patients with end-stage liver disease requiring liver transplantation (lt).
PubMedID- 20513645	coagulopathy in liver diseases.
PubMedID- 24987319	Management of coagulopathy in liver disease.
PubMedID- 25629773	It is defined as acute liver decomposition on the basis of chronic liver disease with mandatory jaundice, coagulopathy and recent development of complications .
PubMedID- 22187658	In “management of coagulopathy in patients with decompensated liver disease”, the authors discussed recent thoughts on coagulation in end-stage liver disease.
PubMedID- 25034295	The approach to the coagulopathy in patients with liver diseases is changing: while the main goal for clinicians so far has been to reduce the risk of bleeding, the results of these new studies highlight the importance of preventing or treating thrombophilic disorders like pvt to avoid microcirculatory damage and eventually liver decompensation.
PubMedID- 23430922	Abnormal glycosylation of coagulation factors and evidence of liver disease are associated with coagulopathy in galactosemic infants.
PubMedID- 20136967	coagulopathy in liver disease: the whole is greater than the sum of its parts.
PubMedID- 22713613	This article reviews the background of coagulopathy in patients with end-stage liver disease and management options and comments on common clinical scenarios.
PubMedID- 21994849	Vitamin k is usually administered to patients who have a prolonged prothrombin time, even though this regimen is typically ineffective because coagulopathy reflects severity of underlying liver disease.
PubMedID- 23533745	Apixaban is contraindicated in patients who have liver disease associated with coagulopathy and a clinically relevant bleeding risk, and in patients who are undergoing concomitant systemic treatment with strong inhibitors of both cytochrome p450 cyp3a4 and p-gp .
PubMedID- 20698945	In our young patient, the combination of neurological disorder, non autoimmune hemolytic anemia and unexplained liver disease along with negative coombs, coagulopathy unresponsive to vitamin k, serum aminotransferases less than 2000 iu/l and normal or markedly subnormal alkaline phosphatase (< 40 iu/l), all suggested wilson's disease.
PubMedID- 20206871	Nevertheless, clinical trials should also be planned to investigate the causal relationship between acquired coagulopathy and bleeding in patients with chronic liver disease.
PubMedID- 22447259	Acute liver failure (alf) (sometimes referred to as fulminant hepatic failure) is a clinical syndrome from a variety of causes resulting from rapid loss in hepatocyte function, typically associated with coagulopathy and encephalopathy in a patient without preexisting liver disease or cirrhosis.
PubMedID- 25068951	Acute liver failure (alf) is an uncommon clinical syndrome that often has a course associated with rapidly progressive multiorgan failure and devastating complications like coagulopathy and encephalopathy in patients without previous liver disease.
PubMedID- 23997457	Rarely a significant coagulopathy in the absence of overt signs of liver disease may be seen in hereditary tyrosinemia.
PubMedID- 26401071	coagulopathy in liver disease: lack of an assessment tool.
PubMedID- 23243422	Treatment of coagulopathy in patients with liver disease is aimed at replacement of deficient clotting factors and may include administration of fresh frozen plasma, cryoprecipitate, prothrombin complex concentrate, rfviia, or platelets .
PubMedID- 26029995	Objectives: acute liver failure is a life-threatening condition with sudden onset liver injury, decreased liver functions, hepatic encephalopathy, and coagulopathy in patients without preexisting liver disease.
PubMedID- 25829903	These ccp may not reflect true coagulopathy in liver disease.
PubMedID- 23561730	coagulopathy in combination with alcoholic liver disease manifests as thrombocytopenia and thrombopathy.

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