PedAM
Pediatric Disease Annotations & Medicines
| Disease | liver disease |
| Symptom | C0005779|coagulation disorders |
| Sentences | 2 |
| PubMedID- 23807858 | The liver plays a central role in the clotting process, and acute and chronic liver diseases are invariably associated with coagulation disorders due to multiple causes: decreased synthesis of clotting and inhibitor factors, decreased clearance of activated factors, quantitative and qualitative platelet defects, hyperfibrinolysis, and accelerated intravascular coagulation.26 patients with liver disease, have a disturbed balance of pro-coagulant and anti-coagulant factors deviating from the normal coagulation cascade.23,27 there is evidence linking coagulation parameters and liver enzymes to clinical outcomes. |
| PubMedID- 22952165 | Common disorders may include thrombocytopaenia, disseminated intravascular coagulation, haemophilia, von willebrand disease, oral anticoagulant therapy or advanced liver disease with associated coagulation disorders. |
Page: 1