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PedAM

Pediatric Disease Annotations & Medicines




Disease leukoplakia
Symptom C0026640|oral cancer
Sentences 5
PubMedID- 24328950 Precancerous lesions, such as leukoplakia, may lead to oral cancers, but the majority of precancerous lesions never undergo malignant transformation.
PubMedID- 22514665 oral cancer development in patients with leukoplakia--clinicopathological factors affecting outcome.
PubMedID- 23473850 Objectives: recent studies have identified podoplanin, a mucin-type transmembrane glycoprotein, as a biomarker for oral cancer risk in patients with oral leukoplakia (opl).
PubMedID- 21743397 Results: salivary il-1beta and il-6 were significantly higher in oral cancer patients than in patients with leukoplakia and control group (p<0.05).
PubMedID- 25552924 Studies have revealed that bmi-1 expression is associated with the development of oral cancer in patients with oral leukoplakia (lp) 14, oral erythroplakia 11, and oral lichen planus 15. in clinical specimens of hnscc, many researchers have found that the overexpression of bmi-1 correlates with poor overall survival 13,16,31. similarly, we also found that the expression of bmi1 was higher in tscc and correlated with a poor overall survival and was also associated with lymph node metastasis and clinical stage.

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