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PedAM

Pediatric Disease Annotations & Medicines




Disease leukemia
Symptom C0021051|immunodeficiency
Sentences 9
PubMedID- 24596581 immunodeficiency due to both leukemia and long periods of chemotherapy exposed the boy at risk of a persistent hev infection.
PubMedID- 25793145 Typical clinical features include ataxia, usually as an early feature, oculomotor apraxia, telangiectasia, immunodeficiency, and increased risk of malignancies such as leukemia and lymphoma.
PubMedID- 24283718 Moreover, t-cell immunodeficiency in leukemia patients may be associated with different causes of immune suppression, such as alterative expression of tcr signaling pathway members and the immune negative feedback regulator a20 .
PubMedID- 25635465 have used b43-pap immunotoxin plus cyclophosphamide to successfully treat human leukemia in mice with severe combined immunodeficiency (scid).
PubMedID- 21189932 Fourteen patients (56%) presented with known underlying medical conditions: congenital heart disease (chd, n=8), immunodeficiency (n=3) due to acute myeloblastic leukemia (aml), myelodysplastic syndrome (mds) and agammaglobulinaemia, and suspected arterial venous malformation (n=1).
PubMedID- 24828872 Investigating and targeting chronic lymphocytic leukemia metabolism with the human immunodeficiency virus protease inhibitor ritonavir and metformin.
PubMedID- 25887663 Of particular relevance to our study, hla-g expression in b cell chronic leukemia correlated with a strong immunodeficiency and poor clinical evolution .
PubMedID- 22368270 Nonobese diabetic/severe combined immunodeficiency mice transplanted with leukemia cells from patients before and during sorafenib resistance recapitulated the clinical results.
PubMedID- 21197387 Ten of these 13 survivors were individuals who developed immunodeficiency because of leukemia or lymphosarcoma treated with chemotherapy.

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