PedAM

Pediatric Disease Annotations & Medicines

Disease	insulinoma
Symptom	C0020598\|hypoglycemia
Sentences	19
PubMedID- 26113980	Everolimus proved to be a viable treatment for hypoglycemia in insulinoma patients and was also proven highly effective in the patients presented here.
PubMedID- 25844345	A diagnosis of insulinoma was suspected in patients with symptomatic fasting hypoglycemia, which includes: (1) symptoms and signs of hypoglycemia, (2) concomitant plasma glucose level of ≤45 mg/dl, and (3) reversibility of symptoms with glucose administration.
PubMedID- 23738155	A case of inoperable malignant insulinoma with resistant hypoglycemia who experienced the most significant clinical improvement with everolimus.
PubMedID- 25892896	Here we report the case of a 79-year-old female who presented with repeated episodes of hypoglycemia and was diagnosed with insulinoma based on laboratory and imaging examinations.
PubMedID- 25381469	Although insulinomas typically present with fasting hypoglycemia, it is important to consider insulinoma in the differential diagnosis of patients presenting exclusively with postprandial hypoglycemia.
PubMedID- 24130355	Further support for this concept derives from recovery of iah and defective counterregulation after eliminating recurrent hypoglycemia in people with insulinoma (13,14) and in people with t1d after pancreas (15,16) and islet cell transplantation (17), as well as through adherence to treatment protocols aimed at meticulous prevention of hypoglycemia (18–21).
PubMedID- 20930440	Glucose-responsive insulinoma in a patient with postprandial hypoglycemia in the morning.
PubMedID- 22844555	insulinoma often presents with symptoms of hypoglycemia caused by an elevation of insulin levels in the blood.
PubMedID- 22525212	To our knowledge, this is the first report to provide evidence that strontium-89 can be useful in controlling intractable hypoglycemia in patients with malignant insulinoma with bone metastases.
PubMedID- 21247848	Conclusion: the orally administered drug everolimus controlled hypoglycemia due to a malignant insulinoma in a patient with prior insulin-requiring diabetes.
PubMedID- 24358830	Furthermore hypoglycemia due to an insulinoma especially in a young age group comes little lower in the list of other possible causes.
PubMedID- 24396652	The main causes of hypoglycemia combined with hyperinsulinemia are insulinoma, inappropriate use of antidiabetic agents, and autoimmune hypoglycemia.
PubMedID- 26107678	However, we believe that hypoglycemia in insulinoma patients is unlikely to produce rbd arising from rem sleep.
PubMedID- 23392213	Background: refractory hypoglycemia in patients with metastatic insulinoma is an important cause of morbidity and mortality.
PubMedID- 21826148	Taken together, these results suggested that inappropriate endogenous hyperinsulinemia was responsible for her hypoglycemia, possibly due to insulinoma, nesidioblastosis, or β cell dysfunction.
PubMedID- 26425596	Attenuated counterregulatory hormonal responses to severe hypoglycemia occur in patients with insulinoma,7-11 in infants with phhi,12,13 and in diabetic patients treated with excess exogenous insulin.14,15 insulinoma resection mitigates hyperinsulinemic hypoglycemic episodes and is associated with restoration of physiologic counterregulatory hormone response to hypoglycemia.7-11 we report 3 individuals who underwent rygb complicated by niphs and subsequently developed adrenal insufficiency (ai).
PubMedID- 23237225	Once hypoglycemia symptoms due to a suspected insulinoma are confirmed, the tumor should be localized prior to attempts at surgical resection.
PubMedID- 25667631	In the case that a patient presents with fasting hypoglycemia, the possibility of an insulinoma should be always considered.
PubMedID- 20052354	Regarding the endocrine function, 6 patients had diabetes mellitus and 2 patients had insulinoma with hypoglycemia preoperatively in organ-preserving pancreatectomy group.

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