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PedAM

Pediatric Disease Annotations & Medicines




Disease idiopathic generalized epilepsy
Symptom C0494475|generalized tonic-clonic seizures
Sentences 5
PubMedID- 20471324 idiopathic generalized epilepsy with generalized tonic-clonic seizures (ige-gtc): a population-based cohort with >20 year follow up for medical and social outcome.
PubMedID- 23859801 The clinical use of lacosamide may broaden, pending results of trials evaluating its use as monotherapy for pos in adults, as treatment for epilepsy in pediatric subjects, and as adjunctive treatment for uncontrolled primary generalized tonic-clonic seizures in those with idiopathic generalized epilepsy.
PubMedID- 25043752 Increased interhemispheric resting-state in idiopathic generalized epilepsy with generalized tonic-clonic seizures: a resting-state fmri study.
PubMedID- 26013703 Levetiracetam was licensed as add-on therapy in children in 2005. nowadays, levetiracetam is registered in europe and the us as add-on therapy for focal onset seizures with or without secondary generalization in patients from 1 month of age, as add-on therapy for myoclonic seizures in patients from 12 years of age with juvenile myoclonic epilepsy, and as add-on therapy for primary generalized tonic-clonic seizures in patients with idiopathic generalized epilepsy (in europe from 12 years of age; in the us from 6 years of age).
PubMedID- 22669118 It is mainly used for the adjunctive treatment of partial-onset seizures in adults and children, as well as myoclonic and primary generalized tonic-clonic seizures in patients with idiopathic generalized epilepsy1,2,3.

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