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PedAM

Pediatric Disease Annotations & Medicines




Disease hypothyroidism
Symptom C0034013|precocious puberty
Sentences 4
PubMedID- 24040602 hypothyroidism with precocious puberty was first described by kendle in 1905 3.
PubMedID- 24251145 Van wyk and grumbach first reported multicystic ovaries with precocious puberty in patients with hypothyroidism in 1960.
PubMedID- 23901203 The clinical syndrome of severe primary hypothyroidism associated with isosexual precocious puberty in females was first described by kendle in 1905.
PubMedID- 23329774 Van wyk-grumbach syndrome is a rare disease characterized by precocious puberty associated with prolonged hypothyroidism and multicystic enlarged ovaries.

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