Disease | hyperuricemia |
Symptom | C0022658|nephropathy |
Sentences | 3 |
PubMedID- 22701621 | In this study, we used streptozotocin (stz)-induced diabetic nephropathy model with hyperuricemia and dyslipidemia in rats, and found over-expression of renal inflammasome components nlrp3, apoptosis-associated speck-like protein and caspase-1, resulting in elevation of il-1beta and il-18, with subsequently deteriorated renal injury. |
PubMedID- 20215410 | In this species, hyperuricemia is associated with gout, nephropathy, and increased cardiovascular disease risk. |
PubMedID- 22557752 | Lesch–nyhan syndrome is an x-linked recessive disorder of purine metabolites leading to hyperuricemia and hyperuricosuria with consequent nephropathy, and neurological effects such as poor muscle control, choreoathetosis, spasticity, self-mutilation, and mental retardation. |
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