PedAM
Pediatric Disease Annotations & Medicines
| Disease | hypersplenism |
| Symptom | C0040034|thrombocytopenia |
| Sentences | 23 |
| PubMedID- 25737395 | We report three cases of peripheral thrombocytopenia due to hypersplenism with a platelet count between 60,000 and 80,000/mm(3), which made it impossible to continue or start a chemotherapy protocol in these patients. |
| PubMedID- 22708981 | Peripheral platelet destruction or sequestration is the major mechanism for thrombocytopenia, with hypersplenism being an important cause. |
| PubMedID- 23275773 | Other chemotherapeutic agents, including 5-fluorodeoxyuridine and irinotecan have also been associated with thrombocytopenia due to hypersplenism but to a much lesser degree than oxaliplatin . |
| PubMedID- 22985446 | Introduction: hypersplenism with thrombocytopenia is a common complication of cirrhosis with portal hypertension. |
| PubMedID- 22771590 | Severe thrombocytopenia due to hypersplenism is a rare complication in sarcoidosis23 which was seen in one patient. |
| PubMedID- 23055649 | other causes of non-immune thrombocytopenia in association with tuberculosis include hypersplenism, thrombotic thrombocytopenic purpura6 and hemophagocytic syndrome. |
| PubMedID- 21734807 | Conclusion: total embolization of the main splenic artery is a safe and feasible procedure and may serve as a supplemental treatment modality for hypersplenism with thrombocytopenia or leukocytopenia accompanying liver cirrhosis. |
| PubMedID- 23833091 | Severe thrombocytopenia due to hypersplenism treated with partial splenic embolisation. |
| PubMedID- 25788181 | Background/purpose: thrombocytopenia due to hypersplenism precludes percutaneous liver biopsy in many cases of chronic liver disease (cld). |
| PubMedID- 24255616 | Lower values ofplatelet counts are seen especially in patients with hs after gastrointestinal bleeding.this was also seen in the current work with the possible cause being the increase ofspleen and hypersplenism leading to frequent thrombocytopenia, leukopenia and anemia. |
| PubMedID- 20467465 | Primary indications for psss were repeated variceal bleeding despite endoscopic therapy (6), symptomatic hypersplenism with thrombocytopenia (2), and liver dysfunction in the setting of hepatic vein thrombosis (2). |
| PubMedID- 22287875 | hypersplenism as a cause of thrombocytopenia may reflect portal hypertension from cirrhosis, collagen vascular disease, or rarely primary neoplasm of the spleen. |
| PubMedID- 22588242 | The theory of portal decompression to improve thrombocytopenia due to hypersplenism has led to the study of transjugular intrahepatic portosystemic shunt (tips) as a potential therapy. |
| PubMedID- 20796158 | Background and aim: thrombocytopenia due to hypersplenism is usually a serious condition in cirrhotic patients who have undergone invasive procedures. |
| PubMedID- 22057175 | A splenectomy was done due to persistent thrombocytopenia associated with hypersplenism, with good response of the platelets counts. |
| PubMedID- 26267788 | In addition, it has been reported that splenomegaly leads to thrombocytopenia, associated with hypersplenism, in more than 60% of patients with hs schistosomiasis, especially in the advanced stages of the disease; however, relatively few patients present symptoms due to hypersplenism and need surgery . |
| PubMedID- 23132324 | The indications for surgery were pain and discomfort caused by a large spleen (5-15 cm below the costal margin) and symptomatic hypersplenism with leucopenia, thrombocytopenia, and anemia. |
| PubMedID- 25879015 | However, sorafenib cannot be used in patients with severe thrombocytopenia, one of the complications of hypersplenism, owing to its platelet-decreasing effect. |
| PubMedID- 25233685 | Indications for surgery were pain and abdominal discomfort caused by spleen enlargement, as well as symptomatic hypersplenism with leucopenia, thrombocytopenia and anemia. |
| PubMedID- 24019767 | Its common symptoms include hepatosplenomegaly, thrombocytopenia due to hypersplenism and bone manifestations. |
| PubMedID- 23781362 | The major problem faced was hypersplenism leading to thrombocytopenia and anemia. |
| PubMedID- 23901200 | hypersplenism may lead to thrombocytopenia, who may present with bleeding similar to our case. |
| PubMedID- 23420139 | While in some patients the disease remained static, in a larger proportion a more severe disease developed characterized by portal hypertension, the latter leading to hypersplenism with neutropenia and thrombocytopenia and, in some cases, to ascites. |
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