PedAM

Pediatric Disease Annotations & Medicines

Disease	hypercalcemia
Symptom	C0020502\|hyperparathyroidism
Sentences	39
PubMedID- 23026597	Conclusions: cinacalcet is an effective alternative for the treatment of hypercalcemia in patients with persistent hyperparathyroidism after kt.
PubMedID- 25861621	hypercalcemia associated with hyperparathyroidism is a common complication after kidney transplantation 1.
PubMedID- 20510722	hypercalcemia associated with primary hyperparathyroidism has frequently resulted in the development of pancreatitis and peptic ulcer disease; however, the pathophysiologic mechanism of this association remains uncertain.
PubMedID- 21391355	Primary hyperparathyroidism as a cause of hypercalcemia in a patient with breast cancer.
PubMedID- 21394466	Elevated pth values may also persist in some patients and hypercalcemia, in combination with hyperparathyroidism, has been traditionally considered a sign of autonomous pth secretion and an indication for parathyroidectomy in transplant recipients .
PubMedID- 23764372	In patients with primary hyperparathyroidism, the state of hyperparathyroid hypercalcemia is associated with reduced muscle strength and impaired quality of life (qol).
PubMedID- 21151209	Diagnosis: severe persistent hyperparathyroidism associated with mild hypercalcemia following renal transplantation.
PubMedID- 22840059	Today, primary hyperparathyroidism usually presents with mild hypercalcemia (within 1 mg/dl above the upper limit of normal), is usually asymptomatic, and diagnosed incidentally on routine investigations for minor non-specific complains.
PubMedID- 23199021	In 1996 a total parathyroidectomy with autotransplantation into the right brachioradial muscle was performed for severe hyperparathyroidism with a pth of 820 pg/ml, hypercalcemia and hyperphosphatemia.
PubMedID- 26019872	Infants that are heterozygous for casr mutations may present neonatal hyperparathyroidism (nhpt) with moderate hypercalcemia and a marked elevation of pth levels, which leads to apparent hyperparathyroid bone disease (1)(2)(3).
PubMedID- 24736147	A 28 year-old girl admitted for a bone tumor of the knee, the blood test shows hypercalcemia with hyperparathyroidism, bone biopsy revealed giant cell lesions characteristic of brown tumors.
PubMedID- 23198183	On july 21, 2012 a 71-year-old caucasian woman with primary hyperparathyroidism awaiting surgery because of significant hypercalcemia and hypercalciuria presented to her local emergency department after acute onset of discomfort within her neck that ran transversely from left to right from the mid to lower neck, sore throat, and difficulty swallowing that had progressively gotten worse over the previous 3 days.
PubMedID- 25505684	hypercalcemia associated with lithium-induced hyperparathyroidism (lih) is a common, but easily overlooked, complication of lithium treatment.
PubMedID- 22876055	Patients with secondary or tertiary hyperparathyroidism, or other causes of hypercalcemia such as malignancy, vitamin d intoxication, immobilization, medications, hyperthyroidism, and other endocrine diseases, were excluded.
PubMedID- 23146456	Persistent hyperparathyroidism associated with hypercalcemia and hyperphosphatemia have been associated with poor graft and patient survivals.
PubMedID- 25641446	hypercalcemia with hyperparathyroidism (hpt) was present in 5 patients and hyperuricemia in 3.
PubMedID- 22577545	In addition to the previous mechanism, several other factors like uremic toxins, increased circulating endogenous nos inhibitors like asymmetric dimethylarginine, secondary hyperparathyroidism leading to hypercalcemia, and increased expression of endothelin a receptors have also been implicated in the pathogenesis of hypertension in ckd.
PubMedID- 23232684	A very rare type of primary hyperparathyroidism with severe hypercalcemia in an infant.
PubMedID- 24251127	We describe a case of hyperparathyroidism with concomitant hypercalcemia accompanied by central pontine myelinosis without hyponatremia/hyperosmolality or associated rapid corrections of sodium, which developed as a consequence of severe hypokalaemia.
PubMedID- 24959180	Cinacalcet (sensipar), a calcimimetic drug, is available for the treatment of secondary hyperparathyroidism associated with renal failure, hypercalcemia in parathyroid cancer, and the treatment of severe hypercalcemia in patients with primary hyperparathyroidism unable to undergo parathyroidectomy .
PubMedID- 24334568	Metastatic calcification occurs in the setting of hypercalcemia, most commonly attributable to hyperparathyroidism, often secondary to renal dysfunction.
PubMedID- 21879659	In primary hyperparathyroidism, repercussions of pronounced hypercalcemia on organs and systems are of essential importance.
PubMedID- 21234416	Most patients with primary hyperparathyroidism are diagnosed because of routine findings of hypercalcemia .
PubMedID- 21286893	A case of acute pancreatitis as a first symptom of primary hyperparathyroidism with severe hypercalcemia is reported.
PubMedID- 25817305	Biochemical tests for malignancy and metabolic disease were negative for all patients except patient 8. initial investigations during her admission had shown normocalcemia, but she was found to have hypercalcemia with possible hyperparathyroidism 1 year after fixation of her peri-implant fracture.
PubMedID- 24736693	Great majority of patients with severe hypercalcemia is attributable to either primary hyperparathyroidism or malignancy.
PubMedID- 22620673	In the neonatal period, homozygous inactivating mutations result in neonatal severe hyperparathyroidism (nshpt) with severe symptomatic hypercalcemia, undermineralized bones, rib cage deformity, and long-bone and rib fractures 3.
PubMedID- 24251163	On follow-up she is diagnosed to have primary hyperparathyroidism with hypercalcemia due to left inferior parathyroid adenoma which improved with intravenous (iv) zolindronic acid therapy and now she is planned to undergo parathyroidectomy.
PubMedID- 22431942	Functional parathyroid cyst: a rare cause of malignant hypercalcemia with primary hyperparathyroidism-a case report and review of the literature.
PubMedID- 25926120	The presence of isolated primary hyperparathyroidism, as a cause of hypercalcemia in cancer patients, has been described in approximately 5-10% of the patients.
PubMedID- 21112866	Although the safety and efficacy of this drug in treating hypercalcemia associated with hyperparathyroidism have not yet been established in clinically controlled trials, its off-label use is not uncommon.
PubMedID- 25741940	Antenatal bartter syndrome presenting as hyperparathyroidism with hypercalcemia and hypercalciuria: a case report and review.
PubMedID- 20145928	If left untreated, hyperparathyroidism can lead to symptoms of hypercalcemia, renal complications, and bone disease connected to hyperparathyroidism, which is characterized by high turnover and remodeling rates leading to osteoporosis and increased fracture risk.
PubMedID- 21660912	Hypocalcemia, frequently seen in the setting of chronic renal insufficiency, results in prolonged st segment and qt interval while hypercalcemia, usually seen with hyperparathyroidism, results in shortening of both intervals.
PubMedID- 23225300	Introduction: hyperparathyroidism often presents with asymptomatic hypercalcemia or minimal, unspecific symptoms and the middle-age female is the predominant population.
PubMedID- 21078161	Parathyroid carcinoma (pc) is a rare cause of primary hyperparathyroidism with characteristic marked hypercalcemia and highly elevated parathyroid hormone levels.
PubMedID- 24251162	Acute pancreatitis due to hypercalcemia associated with hyperparathyroidism (hpt) is not very common.
PubMedID- 23330456	Cinacalcet is also expected to be useful in the treatment of intractable hypercalcemia in patients with primary hyperparathyroidism for whom parathyroidectomy is indicated but surgery is clinically inappropriate or contraindicated.
PubMedID- 20191460	It has long been thought that parathyroidectomy was the only way to solve the problem of stabilized hypercalcemia associated with moderate-severe persistent hyperparathyroidism after kidney transplant.

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